Stem cells and cancer stem cells [electronic resource] : therapeutic applications in disease and injury. Volume 13 / edited by M.A. Hayat.
Hayat, M. A., 1940- editor.
2015
QH588.S83 S74299 2015eb
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Title Stem cells and cancer stem cells [electronic resource] : therapeutic applications in disease and injury. Volume 13 / edited by M.A. Hayat.
ISBN 9789401772334 electronic book
9401772339 electronic book
9789401772327
9401772320
DOI https://doi.org/10.1007/978-94-017-7233-4
Published Dordrecht : Springer, [2015]
Language English
Description 1 online resource (xl, 123 pages) : color illustrations.
Other Standard Identifiers 10.1007/978-94-017-7233-4 doi
Call Number QH588.S83 S74299 2015eb
Dewey Decimal Classification 616.02/774
Summary This is the thirteenth volume in a series which presents current understanding of stem cells and cancer stem cells. This book presents many relevant topics including the different sources of cancer stem cells: the features, roles and clinical potential of stem cells emerge from engaging with this comprehensive work. Chapters explore molecular mechanisms underlying human somatic cell reprogramming to generate induced pluripotent stem cells, and provide expert discussion of the advantages and limitations of applications of some of the stem cell types (pluripotent stem cells, neural stem cells). Many advances are explored, including the importance of stem cell markers in diagnosis, the role of stem cells in angiogenesis and a method for isolating multipotent endothelial-like cells from human adipose tissue, to name a few. Readers will also find a consideration of mathematical models and other quantitative tools which could facilitate research and discovery in the field. The editor's preface to the book and the series is particularly helpful in introducing the work presented in this volume. The detailed overviews, practical experience and insights of international expert authors presented in this handbook will be of value to both professional practitioners and scholars in basic research.
Bibliography, etc. Note Includes bibliographical references and index.
Access Note Access limited to authorized users.
Source of Description Online resource; title from digital title page (viewed on December 07, 2015).
Added Author Hayat, M. A., 1940- editor.
Series Stem Cells and Cancer Stem Cells ; 13.
Available in Other Form Stem cells and cancer stem cells
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Preface; Contents; Contents of Volume 1; Contents of Volume 2; Contents of Volume 3; Contents of Volume 4; Contents of Volume 5; Contents of Volume 6; Contents of Volume 7; Contents of Volume 8; Contents of Volume 9; Contents of Volume 10; Contents of Volume 11; Contents of Volume 12; Contributors; Part I: Treatments; 1: The Use of Mesenchymal Stem Cells for Treating Neurodegenerative Diseases; Introduction; Neurodegeneration; Oxidative Stress; Mitochondrial Dysfunction; Abnormal Cellular Transport Mechanisms; Abnormal Phosphorylation of Key Cellular Molecules; Mesenchymal Stem Cells.

Discovery and Terminology Phenotype; Isolation and Culture; Suitability for Clinical Use; Maldifferentiation and Malignant Transformation; Immunosuppression; Expansion and Biopreservation; Evasion and Migration; Mechanisms of MSC Induced Neuroprotection; Differentiation; Cell Fusion; Mesenchymal Stem Cells' Secretome; Soluble Growth Factors and Enhancement of Endogenous Repair; Anti-oxidants; Extracellular Membrane Vesicles; Angiogenesis; Immunomodulatory Properties; Effect on T Cells; Effect on B Cells; Effect on Dendritic Cells, Macrophages and Natural Killer Cells.

Clinical Application of Mesenchymal Stem Cell TransplantationParkinson's Disease; Multiple Sclerosis; Amyotrophic Lateral Sclerosis; Stroke; Future Strategies and Conclusion; References; 2: HIV Infection and Adipose Tissue Resident Stem Cells: Their Involvement in Pathology and Treatment; Adipose Tissue and Immune System; Human Adipose Tissue Resident Stem Cell (ASC) Localization, Phenotype and Characterization; Adipose Tissue and the Immune Response; Adipose Tissue and HIV Infection; Effect of HIV on ASC; Effect of Antiretroviral Therapy on ASC; Present Clinical Scenarios.

4: Transplantation of Stem Cells to Treat Patients with Multiple SclerosisIntroduction; The Role of Stem Cells in MS Therapy; Different Sources of Stem Cells in MS Therapy; NeuralStem/Precursor Cells (NPCs); Oligodendrocyte Precursor Cells (OPCs); Mesenchymal Stem Cells (MSCs); Timing and Route of Stem Cell Administration; Selection of Patients for Stem Cell Therapy; Future Advances in Stem Cell Transplantation Field; References; 5: Locomotor Recovery After Spinal Cord Transection: Transplantation of Oligodendrocytes and Motoneuron Progenitors from Human Embryonic Stem Cells.

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