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Table of Contents
1. Introduction
Section 1: Basic Science of Free Radical Biology in ENT
2. Free radicals and oxidative stress: Basic concepts and misconceptions
3. A Question of Balance: Free Radicals and Cochlear Homeostasis
4. Antioxidants and their effect on stress-induced pathology in the inner ear
Section 2: Epidemiology of Hearing Loss
5. Role of free radicals in hearing loss due to heavy metals
6. The role of nutrition in healthy hearing: human evidence
Section 3: Oxidative Stress and Noise-Induced Hearing Loss
7. Basic mechanisms underlying noise-induced hearing loss
8. Oxidative stress in noise-induced hearing loss
9. Strategies for evaluating antioxidant efficacy in clinical trials assessing prevention of noise-induced hearing loss
Section 4: Oxidative Stress and Drug-Induced Hearing Loss
10. Aminoglycoside-induced oxidative stress: pathways and protection
11. Hearing loss after cis-platin: oxidative stress pathways and potential for protection
12. Assessment of interventions to prevent drug-induced hearing loss (DIHL)
Section 5: Oxidative Stress and Age-Related Hearing Loss
13. Age-related hearing loss: biochemical pathways and molecular targets
14. Genetics and age-related hearing loss
15. Mechanisms of age-related hearing loss
16. Interventions to prevent age-related hearing loss
Section 6. Hereditary Hearing Loss
17. Genes and hearing loss: relationship to oxidative stress and free radical formation
18. Strategies for the treatment of hereditary hearing loss
Section 7: Cochlear Implants, Radiation, Trauma and Other Stress Factors
19. Loss of Residual Hearing Initiated by Cochlear Implantation: Role of Inflammation-Initiated Cell
20. Role of oxidative stress in sudden hearing loss and Meniere?s disease
Section 8: Head and Neck
21. Role of free radicals in head and neck pathology
22. Free radicals and sleep apnea
23. Free radicals in nasal and paranasal disease
24. Conclusion.
Section 1: Basic Science of Free Radical Biology in ENT
2. Free radicals and oxidative stress: Basic concepts and misconceptions
3. A Question of Balance: Free Radicals and Cochlear Homeostasis
4. Antioxidants and their effect on stress-induced pathology in the inner ear
Section 2: Epidemiology of Hearing Loss
5. Role of free radicals in hearing loss due to heavy metals
6. The role of nutrition in healthy hearing: human evidence
Section 3: Oxidative Stress and Noise-Induced Hearing Loss
7. Basic mechanisms underlying noise-induced hearing loss
8. Oxidative stress in noise-induced hearing loss
9. Strategies for evaluating antioxidant efficacy in clinical trials assessing prevention of noise-induced hearing loss
Section 4: Oxidative Stress and Drug-Induced Hearing Loss
10. Aminoglycoside-induced oxidative stress: pathways and protection
11. Hearing loss after cis-platin: oxidative stress pathways and potential for protection
12. Assessment of interventions to prevent drug-induced hearing loss (DIHL)
Section 5: Oxidative Stress and Age-Related Hearing Loss
13. Age-related hearing loss: biochemical pathways and molecular targets
14. Genetics and age-related hearing loss
15. Mechanisms of age-related hearing loss
16. Interventions to prevent age-related hearing loss
Section 6. Hereditary Hearing Loss
17. Genes and hearing loss: relationship to oxidative stress and free radical formation
18. Strategies for the treatment of hereditary hearing loss
Section 7: Cochlear Implants, Radiation, Trauma and Other Stress Factors
19. Loss of Residual Hearing Initiated by Cochlear Implantation: Role of Inflammation-Initiated Cell
20. Role of oxidative stress in sudden hearing loss and Meniere?s disease
Section 8: Head and Neck
21. Role of free radicals in head and neck pathology
22. Free radicals and sleep apnea
23. Free radicals in nasal and paranasal disease
24. Conclusion.