000746177 000__ 03752cam\a2200481Ii\4500
000746177 001__ 746177
000746177 005__ 20230306141239.0
000746177 006__ m\\\\\o\\d\\\\\\\\
000746177 007__ cr\cn\nnnunnun
000746177 008__ 151201s2015\\\\sz\\\\\\ob\\\\000\0\eng\d
000746177 019__ $$a930836445$$a931591835
000746177 020__ $$a9783034809559$$qelectronic book
000746177 020__ $$a3034809557$$qelectronic book
000746177 020__ $$z9783034809535
000746177 020__ $$z3034809530
000746177 0247_ $$a10.1007/978-3-0348-0955-9$$2doi
000746177 035__ $$aSP(OCoLC)ocn930703232
000746177 035__ $$aSP(OCoLC)930703232$$z(OCoLC)930836445$$z(OCoLC)931591835
000746177 040__ $$aN$T$$beng$$erda$$epn$$cN$T$$dIDEBK$$dEBLCP$$dYDXCP$$dN$T$$dNUI$$dAZU$$dORU$$dCOO$$dOCLCF$$dCDX$$dGW5XE$$dOCLCQ
000746177 049__ $$aISEA
000746177 050_4 $$aQP623.5.S63
000746177 08204 $$a572.88$$223
000746177 24500 $$aCirculating microRNAs in disease diagnostics and their potential biological relevance$$h[electronic resource] /$$cPeter Igaz, editor.
000746177 264_1 $$aBasel :$$bSpringer,$$c2015.
000746177 300__ $$a1 online resource.
000746177 336__ $$atext$$btxt$$2rdacontent
000746177 337__ $$acomputer$$bc$$2rdamedia
000746177 338__ $$aonline resource$$bcr$$2rdacarrier
000746177 4901_ $$aExperientia supplementum ;$$vvolume 106
000746177 504__ $$aIncludes bibliographical references.
000746177 5050_ $$aPart I: General features and technical issues related to circulating microRNA -- 1. Introduction to microRNAs: biogenesis, action, relevance of tissue microRNAs in disease pathogenesis, diagnosis and therapy. The concept of circulating microRNAs -- 2. Extracellular microRNAs in membrane vesicles and non-vesicular carriers -- 3. Technical aspects related to the analysis of circulating microRNAs -- Part II: Diagnostic relevance of circulating microRNAs -- 4. Circulating blood-borne microRNAs as biomarkers in solid tumors -- 5. Circulating microRNA as biomarkers in hematological malignancies -- 6 Circulating microRNAs as biomarkers in cardiovascular diseases -- 7 Circulating microRNAs in neurodegenerative diseases -- 8 Circulating extracellular microRNA in systemic autoimmunity -- 9. Circulating microRNAs in inflammatory bowel diseases -- 10. Circulating microRNAs in diabetes progression: discovery, validation and research translation -- 11. Diagnostic relevance of microRNAs in other body fluids including urine, feces and saliva -- Part III: Potential biological relevance of circulating microRNA -- 12 Circulating microRNAs as hormones -- intercellular and inter-organ conveyors of epigenetic information? -- 13. Are circulating microRNAs involved in tumor surveillance? -- 14.-Hypothetic interindividual and interspecies relevance of microRNAs released in body fluids.
000746177 506__ $$aAccess limited to authorized users.
000746177 520__ $$aMicroRNAs as the endogenous mediators of RNA interference have experienced an unprecedented career in recent years, highlighting their pathogenic, diagnostic and potential therapeutic relevance. Beside tissue microRNAs, they are also found in body fluids, most notably in blood. Significant differences of circulating microRNA levels have been found in various diseases, making them candidates for minimally invasive markers of disease, for example tumor malignancy. The book focuses on the potential diagnostic applicability of circulating microRNAs in various diseases and their potential biological significance.
000746177 588__ $$aOnline resource; title from PDF title page (viewed December 11, 2015).
000746177 650_0 $$aSmall interfering RNA.
000746177 650_0 $$aDiagnosis.
000746177 7001_ $$aIgaz, Peter,$$eeditor.
000746177 77608 $$iPrint version:$$z9783034809535
000746177 830_0 $$aExperientia.$$pSupplementum ;$$vvolume 106.
000746177 85280 $$bebk$$hSpringerLink
000746177 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-0348-0955-9$$zOnline Access$$91397441.1
000746177 909CO $$ooai:library.usi.edu:746177$$pGLOBAL_SET
000746177 980__ $$aEBOOK
000746177 980__ $$aBIB
000746177 982__ $$aEbook
000746177 983__ $$aOnline
000746177 994__ $$a92$$bISE