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Introduction
Protein studies
Electrophoresis and immunofixation
Serum free light chain analysis
Morphology and immunohistochemistry of normal and neoplastic plasma cells
Classification of plasma cell neoplasms
Monoclonal gammopathy of undetermined significance
Plasma cell myeloma
Plasmacytoma? solitary and extraosseus
Monoclonal immunoglobulin deposition diseases
Cytogenetics
Flow cytometry
Integration of laboratory and clinical data into synoptic report
Approaches to treatment, including stem cell transplant
Conclusions
References.

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