Antiepileptic drugs and pregnancy [electronic resource] : a guide for prescribers / MJ Eadie, FJE Vajda.

Preface; Contents; Chapter 1: Introduction; References; Chapter 2: Antiepileptic Drugs and Becoming Pregnant; Achieving Pregnancy; The Situation in the Male; The Situation in the Female; Avoiding Pregnancy; References; Part I: Antiepileptic Drug Pharmacokinetics in Pregnancy; Chapter 3: Antiepileptic Drug Disposition in Pregnancy; Body Changes During Pregnancy; Changes in Physiology; Changes in Biochemistry; Lactation; Drug Disposition in Pregnancy and Lactation; Drug Absorption; Drug Distribution; Drug Elimination; Excretion of Unmetabolised Drug; Drug Metabolism; References

Chapter 4: The Older Antiepileptic DrugsPhenobarbitone; Chemistry; Pharmacodynamics; Pharmacokinetics; Absorption; Distribution; Elimination; Excretion Unchanged; Metabolism; Clinical Pharmacokinetics; Interactions; Adverse Effects; Teratogenicity; Pregnancy; The Mother; The Foetus; Breast Milk ; The Neonate; Phenytoin; Chemistry; Pharmacodynamics; Pharmacokinetics; Absorption; Distribution; Elimination; Excretion Unchanged; Metabolism; Clinical Pharmacokinetics; Interactions; Interactions Altering Phenytoin Concentrations; Phenytoin Affecting Other Substances

Adverse EffectsNervous System; Skin and Gums; Bone; Lymphoid Tissue; Folates; Cardiovascular Effects; Other Effects; Teratogenicity; Pregnancy; The Mother; The Foetus; Breast Milk ; The Neonate; Carbamazepine; Chemistry; Pharmacodynamics; Pharmacokinetics; Absorption; Distribution; Elimination; Excretion Unchanged; Metabolism; Clinical Pharmacokinetics; Interactions; Adverse Effects; Teratogenesis; Pregnancy; The Mother; The Foetus; Breast Milk ; The Neonate; Valproate; Chemistry; Pharmacodynamics; Pharmacokinetics; Absorption; Distribution; Elimination

Excretion UnchangedMetabolism; Clinical Pharmacokinetics; Interactions; Adverse Effects; Teratogenicity; Pregnancy; The Mother; The Foetus; Breast Milk ; The Neonate; References; Chapter 5: Commonly Used Newer Antiepileptic Drugs; Lamotrigine; Chemistry; Pharmacodynamics; Pharmacokinetics; Absorption; Distribution; Elimination; Excretion Unchanged; Metabolism; Clinical Pharmacokinetics; Interactions; Adverse Effects; Teratogenesis; Pregnancy; The Mother; The Foetus; Breast Milk ; The Neonate; Topiramate; Chemistry; Pharmacodynamics; Pharmacokinetics; Absorption

Distribution Elimination; Excretion Unchanged; Metabolism; Clinical Pharmacokinetics; Interactions; Adverse Effects; Teratogenicity; Pregnancy; The Mother; The Foetus; Breast Milk ; The Neonate; Levetiracetam; Chemistry; Pharmacodynamics; Pharmacokinetics; Absorption; Distribution; Elimination; Excretion Unchanged; Metabolism; Clinical Pharmacokinetics; Interactions; Adverse Effects; Teratogenicity; Pregnancy; The Mother; The Foetus; Breast Milk ; The Neonate; References; Chapter 6: Antiepileptic Drugs Sometimes Used in Pregnancy; Oxcarbazepine; Chemistry