000751851 000__ 04933cam\a2200541Ii\4500 000751851 001__ 751851 000751851 005__ 20230306141253.0 000751851 006__ m\\\\\o\\d\\\\\\\\ 000751851 007__ cr\cn\nnnunnun 000751851 008__ 150831t20152016gw\a\\\\o\\\\\001\0\eng\d 000751851 019__ $$a931592516$$a932333434 000751851 020__ $$a9783662472125$$q(electronic book) 000751851 020__ $$a3662472120$$q(electronic book) 000751851 020__ $$z9783662472118 000751851 020__ $$z3662472112 000751851 0247_ $$a10.1007/978-3-662-47212-5$$2doi 000751851 035__ $$aSP(OCoLC)ocn919464449 000751851 035__ $$aSP(OCoLC)919464449$$z(OCoLC)931592516$$z(OCoLC)932333434 000751851 040__ $$aGW5XE$$beng$$erda$$epn$$cGW5XE$$dN$T$$dYDXCP$$dIDEBK$$dEBLCP$$dCDX$$dOCLCA 000751851 049__ $$aISEA 000751851 050_4 $$aRD101 000751851 08204 $$a617.1/5$$223 000751851 24504 $$aThe poly-traumatized patient with fractures$$h[electronic resource] :$$ba multi-disciplinary approach /$$cHans-Christoph Pape, Roy Sanders, Joseph Borrelli, Jr., editors. 000751851 250__ $$aSecond edition. 000751851 264_1 $$aHeidelberg :$$bSpringer,$$c[2015] 000751851 264_4 $$c©2016 000751851 300__ $$a1 online resource (viii, 437pages) :$$billustrations. 000751851 336__ $$atext$$btxt$$2rdacontent 000751851 337__ $$acomputer$$bc$$2rdamedia 000751851 338__ $$aonline resource$$bcr$$2rdacarrier 000751851 500__ $$aIncludes index. 000751851 5050_ $$aPreface; Contents; 1: The Impact of Trauma on Society; 1.1 Introduction; 1.2 The Psychological Implications of Trauma; 1.3 Chronic Pain and Disability Due to Trauma; 1.4 Return to Work After Trauma; 1.5 Global Trends and Perspectives on Trauma; Conclusion; References; 2: Economic Aspects of Trauma Care; 2.1 Introduction; 2.2 Cost of Illness; 2.3 Prevention; 2.4 Economic Evaluation of Health Technologies in Trauma Care; 2.5 Economic Aspects of Multiple/Severe Injuries in Hospital Care; References; 3: Evidence-Based Orthopaedic Trauma Care; 3.1 Origins; 3.2 Present State 000751851 5058_ $$a3.3 Evidence-Based Approach3.3.1 Ask; 3.3.2 Acquire; 3.3.3 Appraise; 3.3.4 Apply; 3.3.5 Act; 3.4 Challenges; 3.5 Future Directions; 3.6 Models for Success in Orthopaedic Trauma Care; 3.7 Origins; 3.8 Formalization and Funding; 3.9 Commitment; 3.10 Research Coordinators; 3.11 Biannual Meetings; 3.12 Operationalization of the EBM Approach; Conclusion; References; 4: Inflammatory Changes and Coagulopathy in Multiply Injured Patients; 4.1 Introduction; 4.2 Damage-Associated Molecular Patterns; 4.3 Acute-Phase Reaction; 4.4 Immune Response After Multiple Injury 000751851 5058_ $$a4.5 Activation and Dysfunction of the Serine Protease Systems4.5.1 The Coagulation System: Coagulopathy; 4.5.2 The Complement System: Complementopathy; 4.5.3 The Kallikrein-Kinin System; 4.6 Cytokines; 4.6.1 Pro-inflammatory Cytokines; 4.6.2 Anti-inflammatory Cytokines; 4.7 Reactive Oxygen Species (ROS); 4.8 Cells Implicated in Multiple Trauma; 4.8.1 Neutrophils; 4.8.2 Monocytes/Macrophages; 4.8.3 Natural Killer Cells; 4.9 Mechanisms of the Development of Organ Dysfunction; 4.9.1 Severity of Initial Injury (First Hit); 4.9.2 Two-Hit Theory; 4.9.3 Ischemia/Reperfusion Injury 000751851 5058_ $$a4.9.4 Barrier Breakdown Conclusion; References; 5: Pathophysiology of Polytrauma; 5.1 Introduction; 5.2 Initial Response; 5.3 Inflammatory Response; 5.4 Clinical Course and Appropriate Actions; 5.5 Clinical Course and Immunomarkers; References; 6: Head Injuries: Neurosurgical and Orthopedic Strategies; 6.1 Introduction; 6.2 Pathophysiology of Head Injury; 6.3 The "Deadly Duo": Hypoxia and Hypotension; 6.4 Clinical Assessment and Management; 6.5 Strategies of Fracture Fixation in Head-Injured Patients; Conclusion; References; 7: Soft Tissue Injuries; 7.1 Introduction 000751851 5058_ $$a7.2 Challenges of Soft Tissue Injury Associated with Fractures7.2.1 Principles and Classifications; 7.2.2 Hypoxia and Perfusion-related Complications; 7.2.2.1 Tissue Hypoxia [11]; 7.2.2.2 Compartment Syndrome; 7.2.2.3 Venous Tissue Congestion and Thrombosis; 7.2.2.4 Decubitus; 7.2.3 Life Threatening Early Wound Infections; 7.3 Surgical Management; 7.3.1 Acute Surgical Management; 7.3.2 Post-acute Surgical Phase; 7.3.3 Early-Intent Defect Coverage; 7.3.4 Peripheral Nerve System; 7.3.4.1 Plexus Injury; 7.3.4.2 Peripheral Nerve Injury; References; 8: Chest Trauma 000751851 506__ $$aAccess limited to authorized users. 000751851 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed August 31, 2015). 000751851 650_0 $$aFractures$$xTreatment. 000751851 650_0 $$aBones$$xWounds and injuries$$xTreatment. 000751851 7001_ $$aPape, Hans-Christoph,$$d1962-$$eeditor. 000751851 7001_ $$aSanders, Roy$$q(Roy W.),$$eeditor. 000751851 7001_ $$aBorrelli, Joseph,$$cJr.,$$eeditor. 000751851 77608 $$iPrint version:$$aPape, Hans-Christoph$$tThe Poly-Traumatized Patient with Fractures : A Multi-Disciplinary Approach$$dBerlin, Heidelberg : Springer Berlin Heidelberg,c2015$$z9783662472118 000751851 852__ $$bebk 000751851 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-662-47212-5$$zOnline Access$$91397441.1 000751851 909CO $$ooai:library.usi.edu:751851$$pGLOBAL_SET 000751851 980__ $$aEBOOK 000751851 980__ $$aBIB 000751851 982__ $$aEbook 000751851 983__ $$aOnline 000751851 994__ $$a92$$bISE