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Atrial fibrillation and stroke epidemiology
Efficacy and limitations of warfarin, and novel oral anticoagulants with AF
Mechanistic rationale for LAA closure with AF and stroke prevention
LAA anatomy
Conventional surgery for LAA closure
The use of transesophageal echocardiography to guide percutaneous LAA closure
The use of intracardiac echocardiography to guide procedural LAA closure
The use of cardiac CTA to guide percutaneous LAA closure
PLAATO device
WATCHMAN device
WATCHMAN: Trials and registries results
Amplatzer Cardiac Plug (ACP) and Amulet
ACP and Amulet: Trials and registries results
LARIAT
LARIAT: Trials and registries results
Novel percutaneous LAA closure devices in clinical or pre-clinical trials
Concomitant AF ablation and LAA closure
Procedural complications and management
Antiplatelet and anticoagulant strategies after LAA closure
Device-related thrombi, residual leaks and consequences.

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