000752775 000__ 03333cam\a2200505Ii\4500 000752775 001__ 752775 000752775 005__ 20230306141432.0 000752775 006__ m\\\\\o\\d\\\\\\\\ 000752775 007__ cr\un\nnnunnun 000752775 008__ 151209s2016\\\\ne\ac\\\ob\\\\000\0\eng\d 000752775 019__ $$a935248144 000752775 020__ $$a9789401774505$$q(electronic book) 000752775 020__ $$a9401774501$$q(electronic book) 000752775 020__ $$z9789401774482 000752775 020__ $$z940177448X 000752775 0247_ $$a10.1007/978-94-017-7450-5$$2doi 000752775 035__ $$aSP(OCoLC)ocn932003238 000752775 035__ $$aSP(OCoLC)932003238$$z(OCoLC)935248144 000752775 040__ $$aYDXCP$$beng$$cYDXCP$$dOCLCO$$dNUI$$dOCLCO$$dAZU$$dCOO$$dOCLCF$$dOCLCQ$$dGW5XE$$dEBLCP$$dOCL 000752775 049__ $$aISEA 000752775 050_4 $$aQH450 000752775 050_4 $$aQH324.2-324.25 000752775 08204 $$a570.285$$223 000752775 24500 $$aTranscriptomics and gene regulation$$h[electronic resource] /$$cJiaqian Wu, Editor ; Honor editor, Dong Kim. 000752775 264_1 $$aDordrecht :$$bSpringer,$$c[2016] 000752775 300__ $$a1 online resource. 000752775 336__ $$atext$$btxt$$2rdacontent 000752775 337__ $$acomputer$$bc$$2rdamedia 000752775 338__ $$aonline resource$$bcr$$2rdacarrier 000752775 4901_ $$aTranslational Bioinformatics ;$$v9 000752775 5050_ $$aThe Analyses of Global Gene Expression and Transcription Factor Regulation -- Global Approaches to Alternative Splicing and its Regulation -- Recent Advances and Open Questions -- Long Non-coding RNAs: Critical Regulators for Cell Lineage Commitment in the Central Nervous System -- Gene expression models of signaling pathways -- From Gene Expression to Disease Phenotypes: Network-Based Approaches to Study Complex Human Diseases -- Introduction to Isoform Sequencing using Pacific Biosciences Technology (Iso-Seq) -- Systematic and Integrative Analysis of Gene Expression to Identify Feature Genes Underlying Human Diseases. 000752775 506__ $$aAccess limited to authorized users. 000752775 520__ $$aThis volume focuses on modern computational and statistical tools for translational gene expression and regulation research to improve prognosis, diagnostics, prediction of severity, and therapies for human diseases. It introduces some of state of the art technologies as well as computational and statistical tools for translational bioinformatics in the areas of gene transcription and regulation, including the tools for next generation sequencing analyses, alternative spicing, the modeling of signaling pathways, network analyses in predicting disease genes, as well as protein and gene expression data integration in complex human diseases etc. The book is particularly useful for researchers and students in the field of molecular biology, clinical biology and bioinformatics, as well as physicians etc. Dr. Jiaqian Wu is assistant professor in the Vivian L. Smith Department of Neurosurgery and Center for Stem Cell and Regenerative Medicine, University of Texas Health Science Centre, Houston, TX, USA. 000752775 650_0 $$aGenetic regulation. 000752775 650_0 $$aLife sciences. 000752775 650_0 $$aGene expression. 000752775 650_0 $$aNeurosciences. 000752775 650_0 $$aBioinformatics. 000752775 7001_ $$aWu, Jiaqian,$$eeditor. 000752775 77608 $$iPrint version:$$z9789401774482$$z940177448X$$w(OCoLC)921236118 000752775 830_0 $$aTranslational bioinformatics ;$$v9. 000752775 852__ $$bebk 000752775 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-94-017-7450-5$$zOnline Access$$91397441.1 000752775 909CO $$ooai:library.usi.edu:752775$$pGLOBAL_SET 000752775 980__ $$aEBOOK 000752775 980__ $$aBIB 000752775 982__ $$aEbook 000752775 983__ $$aOnline 000752775 994__ $$a92$$bISE