000752781 000__ 06410cam\a2200505Ii\4500 000752781 001__ 752781 000752781 005__ 20230306141433.0 000752781 006__ m\\\\\o\\d\\\\\\\\ 000752781 007__ cr\cn\nnnunnun 000752781 008__ 151210t20152016sz\a\\\\o\\\\\001\0\eng\d 000752781 019__ $$a932593562$$a935249469 000752781 020__ $$a9783319250915$$q(electronic book) 000752781 020__ $$a3319250914$$q(electronic book) 000752781 020__ $$z9783319250892 000752781 0247_ $$a10.1007/978-3-319-25091-5$$2doi 000752781 035__ $$aSP(OCoLC)ocn932016680 000752781 035__ $$aSP(OCoLC)932016680$$z(OCoLC)932593562$$z(OCoLC)935249469 000752781 037__ $$a879510$$bMIL 000752781 040__ $$aN$T$$beng$$erda$$epn$$cN$T$$dYDXCP$$dGW5XE$$dN$T$$dOCLCF$$dCDX$$dEBLCP$$dIDEBK$$dNUI$$dCOO$$dOCLCQ 000752781 049__ $$aISEA 000752781 050_4 $$aRK325 000752781 08204 $$a616.3/1$$223 000752781 24500 $$aOral infections and general health$$h[electronic resource] :$$bfrom molecule to chairside /$$cAnne Marie Lynge Pedersen, editor. 000752781 264_1 $$aCham :$$bSpringer,$$c[2015] 000752781 264_4 $$c©2016 000752781 300__ $$a1 online resource (x, 149 pages) :$$billustrations. 000752781 336__ $$atext$$btxt$$2rdacontent 000752781 337__ $$acomputer$$bc$$2rdamedia 000752781 338__ $$aonline resource$$bcr$$2rdacarrier 000752781 500__ $$aIncludes index. 000752781 5050_ $$aAbout the Editor; Contents; Contributors; Part I: Background Topics; 1: Introduction; Part II: Oral Infections and General Health; 2: Dental Caries and General Health in Children and Adults; 2.1 Introduction; 2.2 Link between Caries and General Diseases; 2.3 Common Research Designs; 2.4 Obesity/Overweight; 2.5 Asthma; 2.6 Diabetes; 2.7 Congenital Heart Disease; 2.8 Cancers; 2.9 Cleft Lip Palate; 2.10 Neuropsychiatric Disorders; 2.11 Aging and Cognitive Impairment; 2.12 Caries Management; Conclusions; References. 000752781 5058_ $$a3: Plausible Mechanisms Explaining the Association of Periodontitis with Cardiovascular Diseases3.1 Introduction; 3.2 Definitions of the Conditions; 3.2.1 Periodontitis; 3.2.2 Atherosclerosis and Acute Atherosclerotic Events; 3.3 Bacteremia and Consequences for the Cardiovascular System; 3.4 Immunologic Reactions; 3.5 Pro-inflammatory State; 3.6 Prothrombotic State; 3.7 Dyslipidemia; 3.8 A Common Genetic Background; 3.9 Perspective and Concluding Remarks; References; 4: Linkage Between Periodontal Disease and Diabetes Mellitus; 4.1 Diabetes Mellitus. 000752781 5058_ $$a4.2 Association of Periodontitis and DM4.2.1 Population Data; 4.2.2 Biological Similarities; 4.2.3 Possible Mechanisms of Association; 4.2.4 Outcome of Periodontal Treatment; Conclusion; References; 5: Linkage Between Periodontal Disease and Rheumatoid Arthritis; 5.1 Rheumatoid Arthritis; 5.2 Association of Periodontitis and RA; 5.2.1 Population Data; 5.2.2 Biological Similarities; 5.2.3 Possible Mechanisms of Association; 5.2.4 Outcome of Periodontal Treatment; Conclusion; References; 6: Association Between Dental Infections and Renal and Liver Diseases; 6.1 Introduction. 000752781 5058_ $$a6.2 Renal Diseases6.3 Streptococcal Glomerulonephritis; 6.4 Liver Diseases; Conclusion; References; 7: Association Between Oral Infections and Cancer Risk; 7.1 Introduction; 7.2 Oral and Dental Infections and Cancer Epidemiology; 7.3 Infection-Driven Mechanisms in Carcinogenesis; 7.4 Acetaldehyde Production by Oral Microorganisms; 7.5 Caries, Periodontitis, and Cancer; 7.6 Role of Saliva in the Oral Infection-Linked Carcinogenesis; Conclusion; References; 8: Oral Candidiasis and the Medically Compromised Patient; 8.1 Introduction; 8.2 Clinicopathological Aspects. 000752781 5058_ $$a8.2.1 Histopathology8.2.2 Immunological Aspects; 8.3 Oral Candidiasis in the Medically Compromised Patient; 8.3.1 Oral Candidiasis as Adverse Drug Reaction; 8.3.2 Diabetes Mellitus and Oral Candidiasis; 8.3.3 HIV Infection and Oral Candidiasis; 8.3.4 Recipients of Organ and Haematopoietic Cell Transplants and Cancer Therapy; 8.4 Chronic Mucocutaneous Candidiasis; 8.5 Diagnostic Methods; 8.5.1 Culture of Clinical Samples in Order to Quantify and Identify the Candida Load; 8.5.2 Smears; 8.5.3 Biopsy; 8.5.4 Molecular Techniques for Candida Identification; References. 000752781 506__ $$aAccess limited to authorized users. 000752781 520__ $$aThis book provides a wide-ranging update on the associations between oral infections and general health. Detailed consideration is given to the underlying mechanisms and pathways linking oral infections to general health, including metastatic spread of infection from the oral cavity as a result of transient bacteremia, metastatic injury from the effects of circulating oral microbial toxins, and metastatic inflammation caused by immunological dysfunction induced by oral microorganisms. The book also reviews the complex structure and development of oral biofilms in health and disease, and the molecular tools that are currently available for their analysis. The advantages and limitations of such techniques, as well as their impact on the future of diagnostics, prevention, and patient management, are discussed. The most common oral diseases can have significant implications for general health. For example, chronic oral infections, especially periodontitis, have been associated with diabetes, cardiovascular disease, and low birth weight. The microbial pathogenesis and etiology of dental caries, gingivitis, and chronic periodontitis have been comprehensively studied, and it is now generally accepted that these diseases occur as a result of the concerted actions of several microbial communities. In this regard, both the quantity and the quality of saliva play an essential role as the oral microbial composition and growth conditions are influenced by numerous salivary antimicrobial factors. Oral biofilms are complex and vary widely in composition, but improved knowledge of these biofilms holds the key to greater understanding of the disease processes and consequently the development of new preventive and therapeutic strategies. 000752781 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed December 17, 2015). 000752781 650_0 $$aMouth$$xInfections. 000752781 7001_ $$aPedersen, Anne Marie Lynge,$$eeditor. 000752781 77608 $$iPrint version:$$aPedersen, Anne Marie Lynge.$$tOral Infections and General Health : From Molecule to Chairside.$$dCham : Springer International Publishing, ©2016$$z9783319250892 000752781 852__ $$bebk 000752781 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-25091-5$$zOnline Access$$91397441.1 000752781 909CO $$ooai:library.usi.edu:752781$$pGLOBAL_SET 000752781 980__ $$aEBOOK 000752781 980__ $$aBIB 000752781 982__ $$aEbook 000752781 983__ $$aOnline 000752781 994__ $$a92$$bISE