Dimeric Sesquiterpenoids; 1 Introduction; 2 Classification and Distribution; 2.1 Disesquiterpenoid DSs; 2.1.1 Bisabolane Disesquiterpenoids; 2.1.2 Germacrane Disesquiterpenoids; 2.1.3 Guaiane, Pseudoguaiane, and Xanthane Disesquiterpenoids; 2.1.4 Eremophilane Disesquiterpenoids; 2.1.5 Cadinane Disesquiterpenoids; 2.1.6 Eudesmane Disesquiterpenoids; 2.1.7 Lindenane Disesquiterpenoids; 2.1.8 Cuparane, Cyclolaurane, and Herbertane Disesquiterpenoids; 2.1.9 Miscellaneous Disesquiterpenoids; 2.1.10 Compound Disesquiterpenoids; 2.2 Pseudo-disesquiterpenoids

2.2.1 Dimeric Aza-sesquiterpenoids2.2.2 Miscellaneous Pseudo-disesquiterpenoids; 3 Structural Elucidation; 3.1 General; 3.2 Mass Spectrometry; 3.3 Nuclear Magnetic Resonance Spectroscopy; 3.4 Single-Crystal X-Ray Diffraction; 3.5 CD and ECD Calculations; 3.6 Chemical Methods; 3.7 Structural Elucidation of Serratustone A; 4 Biological Activity; 4.1 Cytotoxic and Antitumor Activity; 4.2 Anti-inflammatory Activity; 4.3 Immunosuppressive Activity; 4.4 Potassium Channel Blocking and Cardiovascular Activity; 4.5 Antimalarial, Antiprotozoal, Antibacterial, Antifungal, and Antiviral Activity

4.6 Neurotrophic Activity4.7 Miscellaneous Activities; 5 Synthesis; 5.1 Biogenesis; 5.1.1 [4+2] Diels-Alder Reactions; 5.1.2 [2+2] Cycloaddition and [6+6] Cycloaddition; 5.1.3 Radical Reactions; 5.1.4 Aldol Reactions; 5.1.5 Esterification, Etherification, and Acetal-Formation Reactions; 5.1.6 Dimerization Through a Linker; 5.1.7 Michael-Type Reactions; 5.2 Chemical Synthesis; 5.2.1 Diels-Alder Cycloaddition; 5.2.2 Oxidative Coupling; 5.2.3 Dimerization with Linkers; 5.2.4 Miscellaneous Dimerization Methods; 6 Conclusions; References; Acetogenins from Annonaceae; 1 Introduction

2 Annonaceous Acetogenins in the Plant Kingdom3 Classification of Annonaceous Acetogenins (Since 1997 Until the End of 2014); 3.1 Linear and Epoxy Annonaceous Acetogenins; 3.2 Mono-THF Annonaceous Acetogenins, Including Derivatives with a Mono-THF Ring; 3.3 Bis-THF Annonaceous Acetogenins, Including Derivatives with Adjacent or Non-adjacent Bis-THF Rings; 3.4 Miscellaneous; 4 Chemotaxonomy of the Annonaceae Family; 5 Synthesis of Annonaceous Acetogenins; 5.1 Linear Annonaceous Acetogenins; 5.1.1 Montecristin; 5.1.2 (-)-Muricatacin; 5.1.3 Tonkinelin; 5.2 Mono-THF Annonaceous Acetogenins

5.3 Adjacent Bis-THF Annonaceous Acetogenins5.4 Non-adjacent Bis-THF Annonaceous Acetogenins; 5.5 Other AGEs; 5.5.1 Adjacent Type THF-THP AGEs; 5.5.2 Non-adjacent THF-THP Type; 5.5.3 THP Type; 5.5.4 Tri-THF Type; 5.5.5 Bis-lactone Type; 6 Biological Activity and Mechanism of Action of Annonaceous Acetogenins; 6.1 Pesticidal Activities; 6.2 Cytotoxic, Cancer-Related, and Ionophore Activities (Anticancer Activity); 6.3 Neurotoxic Activities; 6.4 Other Activities; 6.4.1 Anti-inflammatory Effects; 6.4.2 Promotion of Biofilm Formation in Microbes; 6.4.3 Interaction of AGEs with Membranes