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000752919 019__ $$a935250762
000752919 020__ $$a9783319239927$$q(electronic book)
000752919 020__ $$a3319239929$$q(electronic book)
000752919 020__ $$z9783319239903
000752919 0247_ $$a10.1007/978-3-319-23992-7$$2doi
000752919 035__ $$aSP(OCoLC)ocn932198494
000752919 035__ $$aSP(OCoLC)932198494$$z(OCoLC)935250762
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000752919 049__ $$aISEA
000752919 050_4 $$aQD96.R34
000752919 08204 $$a543.57$$223
000752919 1001_ $$aProcházka, Marek,$$eauthor.
000752919 24510 $$aSurface-enhanced raman spectroscopy$$h[electronic resource] :$$bbioanalytical, biomolecular and medical applications /$$cMarek Procházka.
000752919 264_1 $$aCham :$$bSpringer,$$c2016.
000752919 300__ $$a1 online resource :$$bchiefly color illustrations.
000752919 336__ $$atext$$btxt$$2rdacontent
000752919 337__ $$acomputer$$bc$$2rdamedia
000752919 338__ $$aonline resource$$bcr$$2rdacarrier
000752919 4901_ $$aBiological and medical physics, biomedical engineering,$$x2197-5647
000752919 504__ $$aIncludes bibliographical references and index.
000752919 5050_ $$aPreface; Contents; Acronyms; 1 Introduction; References; 2 Basics of Raman Scattering (RS) Spectroscopy; Abstract; 2.1 Short History of Raman Effect; 2.2 Basic Theory of RS; 2.3 Molecular Vibrations and Their Raman Activity; 2.4 Raman Experiment; 2.5 Raman Spectroscopy for Biomolecular Studies; 3 Basics of Surface-Enhanced Raman Scattering (SERS); Abstract; 3.1 SERS Mechanisms; 3.1.1 EM Mechanism of SERS; 3.1.2 Chemical (Molecular) Mechanism of SERS; 3.2 SERS EFs; 3.3 SM-SERS; 3.4 SERS-Active Substrates; 3.4.1 Metallic NP Hydrosols.
000752919 5058_ $$a3.4.2 NPs and Nanostructures on Planar Supports Prepared by Bottom-Up Techniques3.4.2.1 NPs Self-assembled in Planar Supports; 3.4.2.2 Metallic NR Arrays Prepared by Angle Vapour Deposition; 3.4.3 Nanostructures Fabricated Using Nanolithographic (Top-Down) Techniques; 3.4.3.1 Electron Beam Lithography (EBL) and Ion Beam Lithography (IBL); 3.4.3.2 Nanoimprint Lithography (NIL); 3.4.4 Highly Ordered Metallic Nanostructures Fabricated by Template Techniques; 3.4.4.1 Nanosphere Lithography (NSL); 3.4.4.2 ``Hole Mask'' Colloidal Lithography (HCL); 3.4.4.3 Electrochemical Depositions.
000752919 5058_ $$a3.4.5 Commercially Available Substrates3.5 Practical Aspects of SERS; 3.6 Related Enhanced Techniques; References; 4 Bioanalytical SERS Applications; Abstract; 4.1 Quantitative SERS Methods; 4.1.1 SERS-Active Substrates for Quantitative SERS; 4.1.2 Internal Intensity Standards for Quantitative SERS; 4.1.3 Sensitivity and Specificity of SERS Sensor; 4.2 SERS Sensing of Pharmaceuticals and Drugs; 4.2.1 SERS Sensing of Pharmaceuticals; 4.2.2 SERS Sensing of Drugs; 4.3 SERS Sensing of Pollutants, Food Contaminants and Food Additives; 4.3.1 SERS Sensing of Pollutants and Pesticides.
000752919 5058_ $$a4.3.2 SERS Sensing of Melamine4.3.3 SERS Sensing of Food Colourants; 4.4 SERS Identification of Biowarfare Agent Anthrax; References; 5 Biomolecular SERS Applications; Abstract; 5.1 SERS Biomolecular Detection Schemes; 5.2 Nucleic Acids (NAs) and Their Components; 5.2.1 Intrinsic Detection of NAs; 5.2.2 Intrinsic NA Detection Using Hybridization; 5.2.3 Intrinsic NA Detection Using TERS; 5.2.4 Extrinsic Detection of NAs; 5.2.5 Extrinsic NA Detection Using Hybridization; 5.3 Proteins and Their Components; 5.3.1 Intrinsic Detection of Proteins; 5.3.2 Extrinsic Detection of Proteins.
000752919 5058_ $$a5.3.3 Immunoassays5.4 Lipids and Membranes; References; 6 SERS Investigations of Cells, Viruses and Microorganisms; Abstract; 6.1 Intracellular SERS Investigations; 6.1.1 Intracellular SERS Detection Strategies; 6.1.2 Delivery of the Metallic NPs Inside the Cells; 6.1.3 Chemical Probing in Cells by Intrinsic SERS Spectra; 6.1.4 Chemical Probing in Cells Using SERS Tags with RRMs; 6.1.5 Endosomal pH Monitored by SERS; 6.1.6 Intracellular SERS Using Tip-like Substrates; 6.1.7 Experimental Aspects of Intracellular SERS Studies; 6.2 Detection and Identification of Viruses and Microorganisms.
000752919 506__ $$aAccess limited to authorized users.
000752919 520__ $$aThis book gives an overview of recent developments in RS and SERS for sensing and biosensing considering also limitations, possibilities and prospects of this technique. Raman scattering (RS) is a widely used vibrational technique providing highly specific molecular spectral patterns. A severe limitation for the application of this spectroscopic technique lies in the low cross section of RS. Surface-enhanced Raman scattering (SERS) spectroscopy overcomes this problem by 6-11 orders of magnitude enhancement compared with the standard RS for molecules in the close vicinity of certain rough metal surfaces. Thus, SERS combines molecular fingerprint specificity with potential single-molecule sensitivity. Due to the recent development of new SERS-active substrates, labeling and derivatization chemistry as well as new instrumentations, SERS became a very promising tool for many varied applications, including bioanalytical studies and sensing. Both intrinsic and extrinsic SERS biosensing schemes have been employed to detect and identify small molecules, nucleic acids and proteins, and also for cellular and in vivo sensing.
000752919 588__ $$aOnline resource; title from PDF title page (viewed December 17, 2015).
000752919 650_0 $$aRaman spectroscopy.
000752919 650_0 $$aRaman effect, Surface enhanced.
000752919 77608 $$iPrint version:$$z9783319239903
000752919 830_0 $$aBiological and medical physics, biomedical engineering.
000752919 852__ $$bebk
000752919 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-23992-7$$zOnline Access$$91397441.1
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000752919 980__ $$aEBOOK
000752919 980__ $$aBIB
000752919 982__ $$aEbook
000752919 983__ $$aOnline
000752919 994__ $$a92$$bISE