000753064 000__ 03640cam\a2200481Ii\4500
000753064 001__ 753064
000753064 005__ 20230306141537.0
000753064 006__ m\\\\\o\\d\\\\\\\\
000753064 007__ cr\cn\nnnunnun
000753064 008__ 151222t20152016sz\a\\\\o\\\\\001\0\eng\d
000753064 019__ $$a932593610
000753064 020__ $$a9783319247809$$q(electronic book)
000753064 020__ $$a3319247808$$q(electronic book)
000753064 020__ $$z9783319247786
000753064 0247_ $$a10.1007/978-3-319-24780-9$$2doi
000753064 035__ $$aSP(OCoLC)ocn933293453
000753064 035__ $$aSP(OCoLC)933293453$$z(OCoLC)932593610
000753064 037__ $$a879507$$bMIL
000753064 040__ $$aGW5XE$$beng$$erda$$epn$$cGW5XE$$dOCLCF$$dIDEBK$$dYDXCP$$dNUI$$dCOO$$dOCLCQ$$dEBLCP
000753064 049__ $$aISEA
000753064 050_4 $$aQP609.A3
000753064 08204 $$a572/.7553$$223
000753064 24500 $$aRegulation of Ca2+-ATPases, V-ATPases and F-ATPases$$h[electronic resource] /$$cedited by Sajal Chakraborti, Naranjan S. Dhalla.
000753064 264_1 $$aCham :$$bSpringer,$$c[2015]
000753064 264_4 $$c©2016
000753064 300__ $$a1 online resource (xiii, 586 pages) :$$billustrations.
000753064 336__ $$atext$$btxt$$2rdacontent
000753064 337__ $$acomputer$$bc$$2rdamedia
000753064 338__ $$aonline resource$$bcr$$2rdacarrier
000753064 4901_ $$aAdvances in biochemistry in health and disease ;$$vvolume 14
000753064 500__ $$aIncludes index.
000753064 506__ $$aAccess limited to authorized users.
000753064 520__ $$aThe biological membranes of cellular organization enfold an important group of membrane proteins called the ATPases, which are not only versatile in maintaining chemical gradient and electrical potential across the membrane but also bring metabolites necessary for cell metabolism and drive out toxins, waste products and solutes that otherwise can curb cell functions. ATPases are distributed virtually in all live forms starting from unicellular to multicellular and also in viruses. There are different types of ATPases, which differ in function and structure and in the type of ions they transport. The three main types of the ion pump ATPase family are: (i) P-type ATPases that transport different ions across membranes and Ca2+ATPases belongs to this catagory (ii) F-type ATPase in mitochondria, chloroplasts and bacterial plasma membranes produce ATP using the proton gradient; and (iii) V-type ATPase catalyzes ATP hydrolysis to transport solutes and maintains acidic pH in organelles like lysosomes. Genetic defects in either of the ATPases cause several diseases and a number of researches have demonstrated the involvement of the members of ATPases in the cell pathology and diseases, thereby penetrating exciting new areas of our understanding. In this book, the authors summarize recent knowledge about the molecular mechanisms associated with Ca2+-ATPase, V-ATPase and F-ATPase in intracellular and extracellular Ca2+ transport, mitochondrial ATP synthase, vesicular H+ transport, and lysosomal pH regulation. This book thereby bridges the gap between fundamental research and biomedical and pharmaceutical applications. The book provides an informative resource to improve ATPase research and modern therapeutic approaches toward different life threatening diseases that are associated with dysregulation of the ATPases.
000753064 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed December 21, 2015).
000753064 650_0 $$aAdenosine triphosphatase.
000753064 7001_ $$aChakraborti, Sajal,$$eeditor.
000753064 7001_ $$aDhalla, Naranjan S.,$$eeditor.
000753064 77608 $$iPrint version:$$z9783319247786
000753064 830_0 $$aAdvances in biochemistry in health and disease ;$$vvolume 14.
000753064 852__ $$bebk
000753064 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-24780-9$$zOnline Access$$91397441.1
000753064 909CO $$ooai:library.usi.edu:753064$$pGLOBAL_SET
000753064 980__ $$aEBOOK
000753064 980__ $$aBIB
000753064 982__ $$aEbook
000753064 983__ $$aOnline
000753064 994__ $$a92$$bISE