000753312 000__ 06221cam\a2200541Ii\4500
000753312 001__ 753312
000753312 005__ 20230306141551.0
000753312 006__ m\\\\\o\\d\\\\\\\\
000753312 007__ cr\cn\nnnunnun
000753312 008__ 160113s2016\\\\sz\a\\\\o\\\\\001\0\eng\d
000753312 019__ $$a933784345$$a934046272$$a935256196
000753312 020__ $$a9783319253046$$q(electronic book)
000753312 020__ $$a3319253042$$q(electronic book)
000753312 020__ $$z9783319253022
000753312 020__ $$z3319253026
000753312 0247_ $$a10.1007/978-3-319-25304-6$$2doi
000753312 035__ $$aSP(OCoLC)ocn934627979
000753312 035__ $$aSP(OCoLC)934627979$$z(OCoLC)933784345$$z(OCoLC)934046272$$z(OCoLC)935256196
000753312 040__ $$aGW5XE$$beng$$erda$$epn$$cGW5XE$$dYDXCP$$dNUI$$dN$T$$dCDX$$dEBLCP$$dIDEBK
000753312 049__ $$aISEA
000753312 050_4 $$aQR151
000753312 08204 $$a579.5/62$$223
000753312 24500 $$aYeast membrane transport$$h[electronic resource] /$$cJosé Ramos, Hana Sychrová, Maik Kschischo, editors.
000753312 264_1 $$aCham :$$bSpringer,$$c2016.
000753312 300__ $$a1 online resource (viii, 379 pages) :$$billustrations.
000753312 336__ $$atext$$btxt$$2rdacontent
000753312 337__ $$acomputer$$bc$$2rdamedia
000753312 338__ $$aonline resource$$bcr$$2rdacarrier
000753312 4901_ $$aAdvances in experimental medicine and biology,$$x0065-2598 ;$$vvolume 892
000753312 500__ $$aIncludes index.
000753312 5050_ $$aPreface; Contents; 1 Membrane Transport in Yeast, An Introduction; 1.1 Importance of Membrane Transport Processes; 1.2 Why Yeast?; 1.3 A Bit of "History"; 1.4 Mechanistic Processes Involved in Membrane Transport; 1.5 A Comment on Intracellular Membranes; 1.6 Are There Still New Interesting Discoveries in Yeast?; 1.7 Basic Versus Applied Research in Membrane Transport; 1.8 Overview of the Contributions; References; 2 Cell Surface Interference with Plasma Membrane and Transport Processes in Yeasts; 2.1 Introduction; 2.2 An Overview of the Structure and Biophysical Properties of Yeast Cell Wall
000753312 5058_ $$a2.3 Cell Wall Porosity and Impact for Material Exchange2.4 Biosorbant and Selective Molecular Sieve Properties of the Yeast Cell Wall; 2.5 Inference of Cell Wall in Metal Ions Uptake and Ionome Homeostasis; 2.6 Inference of Cell Wall with Membrane Fluidity and Transport Processes from Genome Scale Analyses; 2.7 Summing Up; References; 3 Proton Transport and pH Control in Fungi; 3.1 Introduction; 3.2 The Physiological Context of pH Homeostasis in S. cerevisiae; 3.3 The Plasma Membrane H+-pump Pma1 and Organellar V-ATPases: Central Players in Cellular pH Control
000753312 5058_ $$a3.3.1 Pma1 Structure, Function, and Genetics3.3.2 V-ATPases: Structure, Function, and Genetics; 3.3.3 Regulation of Pma1; 3.3.4 Regulation of V-ATPases; 3.3.5 Coordination of V-ATPase and Pma1 Activity; 3.3.6 Other Regulators of Cellular pH in Yeast; 3.4 Genomic Perspectives on H+-Transport and pH Control; 3.4.1 pH Measurements Across Deletion Mutant Arrays; 3.4.2 A Systems-Level View of Cytosolic pH Control; 3.4.3 A Systems-Level View of Vacuolar pH Control; 3.4.4 Cellular Responses to pH Stress; 3.5 pH as a Growth Signal in S. cerevisiae; 3.6 Proton Transport and pH Control in Other Fungi
000753312 5058_ $$a3.6.1 V-ATPase and Pma1 in Neurospora crassa3.6.2 pH Control in Pathogenic Fungi; 3.7 Conclusions and Future Directions; References; 4 Function and Regulation of Fungal Amino Acid Transporters: Insights from Predicted Structure; 4.1 Introduction; 4.2 Classification of Fungal Amino Acid Transporters; 4.3 Structure-Function Relationships and Determination of Specificity in the YAT Family; 4.3.1 The YAT-Family Proteins Adopt the LeuT Fold; 4.3.2 Using Structural Models to Study Substrate Binding and Translocation in YATs; 4.3.2.1 Residues Mediating Recognition of the Amino-Acid Backbone
000753312 5058_ $$a4.3.2.2 Residues in Several TMs Mediate Recognition of Amino Acid Side Chains4.3.2.3 Role of Proximal and Middle Gate Residues; 4.3.2.4 Role of Distal Gate Residues; 4.3.3 Genetically Isolated Specificity-Affecting YAT Mutants Altered in TM Domains; 4.3.4 Role of Intracellular and Extracellular Loops in Substrate Selectivity; 4.3.5 Summary; 4.4 Substrate-Mediated Endocytosis; 4.4.1 Inhibition of Transporters by Selective Endocytosis: General Principles; 4.4.2 Substrate-Induced Endocytosis of Fungal Amino Acid Transporters
000753312 506__ $$aAccess limited to authorized users.
000753312 520__ $$aThis contributed volume reviews the recent progress in our understanding of membrane transport in yeast including both Saccharomyces cerevisiae and non-conventional yeasts. The articles provide a summary of the key transport processes and put these in a systems biology context of cellular regulation, signal reception and homeostasis. After a general introduction, readers will find review articles covering the mechanisms and regulation of transport for various substrates ranging from diverse nutrients to cations, water and protons. These articles are complemented by a chapter on extremophilic yeast, a chapter on the mathematical modelling of ion transport and two chapters on the role of transport in pathogenic yeasts and antifungal drug resistance. Each article provides both a general overview of the main transport characteristics of a specific substrate or group of substrates and the unique details that only an expert working in the field is able to transmit to the reader. Researchers and students of the topic will find this book to be a useful resource for membrane transport in yeast collecting information in one complete volume, which is otherwise scattered across many papers. This might also be interesting for scientists investigating other species in order to compare transport mechanisms with known functions in yeast with the cells on which they work.
000753312 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed January 12, 2016).
000753312 650_0 $$aYeast$$xPhysiological transport.
000753312 7001_ $$aRamos, José,$$eeditor.
000753312 7001_ $$aSychrová, Hana,$$eeditor.
000753312 7001_ $$aKschischo, Maik,$$eeditor.
000753312 77608 $$iPrint version:$$z3319253026$$z9783319253022$$w(OCoLC)920447047
000753312 830_0 $$aAdvances in experimental medicine and biology ;$$vv.892.
000753312 852__ $$bebk
000753312 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-25304-6$$zOnline Access$$91397441.1
000753312 909CO $$ooai:library.usi.edu:753312$$pGLOBAL_SET
000753312 980__ $$aEBOOK
000753312 980__ $$aBIB
000753312 982__ $$aEbook
000753312 983__ $$aOnline
000753312 994__ $$a92$$bISE