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000753399 019__ $$a934886706
000753399 020__ $$a9783319256160$$q(electronic book)
000753399 020__ $$a3319256165$$q(electronic book)
000753399 020__ $$z9783319256146
000753399 020__ $$z3319256149
000753399 0247_ $$a10.1007/978-3-319-25616-0$$2doi
000753399 035__ $$aSP(OCoLC)ocn935330699
000753399 035__ $$aSP(OCoLC)935330699$$z(OCoLC)934886706
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000753399 049__ $$aISEA
000753399 050_4 $$aRC685.H8
000753399 08204 $$a616.1/32$$223
000753399 24500 $$aHypertension and the brain as an end-organ target$$h[electronic resource] /$$cHélène Girouard, editor.
000753399 264_1 $$aCham :$$bSpringer,$$c2016.
000753399 300__ $$a1 online resource (xix, 221 pages) :$$billustrations.
000753399 336__ $$atext$$btxt$$2rdacontent
000753399 337__ $$acomputer$$bc$$2rdamedia
000753399 338__ $$aonline resource$$bcr$$2rdacarrier
000753399 5050_ $$aA systematic review of reviews to examine the association between hypertension and cognitive impairments in adults -- Hypertension and age-related cognitive decline -- Hypertension and stroke -- Neuroimaging as a research tool in human essential hypertension -- Cognitive Dysfunction and Dementia in animal models of hypertension -- The effects of hypertension on cerebral artery structure and function, and cerebral blood flow -- Arterial stiffness and the brain -- Endothelium, the blood-brain barrier, and hypertension -- Hypertension and brain inflammation: role of RAS-induced glial activation -- Sex differences in neural regulation of hypertension.
000753399 506__ $$aAccess limited to authorized users.
000753399 520__ $$aThe first comprehensive overview of the effects of hypertension on the brain. The book discusses not only the relationship between hypertension and stroke, but also the much less studied relationship between hypertension and cognitive decline and neurodegenerative diseases such as Alzheimer's. It seeks to answer two important questions. First, what are the conditions under which hypertension is associated with stroke, cognitive decline, and neurodegenerative disease? And second, what are the biological mechanisms by which hypertension alters brain homeostasis? By looking at the biological mechanisms of these relationships, this book provides insight to neuroscientists and neurologists regarding why anti-hypertension treatments make a big difference in the case of stroke, but have very little impact on cognitive decline and brain aging.
000753399 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed January 20, 2016).
000753399 650_0 $$aHypertension$$xComplications.
000753399 650_0 $$aTarget organs (Anatomy)
000753399 7001_ $$aGirouard, Hélène,$$eeditor.
000753399 77608 $$iPrint version:$$z3319256149$$z9783319256146$$w(OCoLC)921235926
000753399 852__ $$bebk
000753399 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-25616-0$$zOnline Access$$91397441.1
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000753399 980__ $$aEBOOK
000753399 980__ $$aBIB
000753399 982__ $$aEbook
000753399 983__ $$aOnline
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