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000753513 019__ $$a937404452
000753513 020__ $$a9784431559399$$q(electronic book)
000753513 020__ $$a4431559396$$q(electronic book)
000753513 020__ $$z9784431559375
000753513 0247_ $$a10.1007/978-4-431-55939-9$$2doi
000753513 035__ $$aSP(OCoLC)ocn936176558
000753513 035__ $$aSP(OCoLC)936176558$$z(OCoLC)937404452
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000753513 08204 $$a616.994042$$223
000753513 24500 $$aGlycosignals in cancer$$h[electronic resource] :$$bmechanisms of malignant phenotypes /$$cKoichi Furukawa, Minoru Fukuda, editors.
000753513 264_1 $$aTokyo :$$bSpringer,$$c[2016]
000753513 264_4 $$c©2016
000753513 300__ $$a1 online resource :$$bcolor illustrations
000753513 336__ $$atext$$btxt$$2rdacontent
000753513 337__ $$acomputer$$bc$$2rdamedia
000753513 338__ $$aonline resource$$bcr$$2rdacarrier
000753513 504__ $$aIncludes bibliographical references.
000753513 5050_ $$aPart 1 Changes of Glycosylation Machineries in Cancer Cells -- 1 Roles of Fucosyltransferases in Cancer Phenotypes -- 2 Glycosyltransferases and Gastric Cancer -- Part 2 Regulation of Cancer Phenotypes by Carbohydrates -- 3 Differential Roles of Mammalian Sialidases in Cancers -- Part 3 Altered Cell Signaling in Cancer Cells -- 4 Regulatory Mechanisms for Malignant Properties of Cancer Cells with Disialyl and Monosialyl Gangliosides -- 5 Regulation of Growth Factor Receptors by Glycosphingolipids -- 6 Nutrient Regulation of Cancer Cells by O-GlcNAcylation -- Part 4 Regulation of Immune Systems and Cancers by Carbohydrates -- 7 Function of Unique O-Glycan Structures in Protecting Gastric Mucosa Against Helicobacter pylori Infection and Gastric Cancer Development -- 8 Sialylation and Immune Surveillance of Cancer by Siglecs -- Part 5 Changes in the Organization of Complex Carbohydrates in Cancers -- 9 Expression and Function of Poly-N-Acetyllactosamine Type Glycans in Cancer -- 10 Role of Glycans in Cancer Cell Death: A Deadly Relationship -- Part 6 Implication of Sugars in Cancer Diagnostics and Therapeutics -- 11 Targeting Glycans for Immunotherapy of Human Cancers.
000753513 506__ $$aAccess limited to authorized users.
000753513 520__ $$aThis book is a collection of cutting-edge studies on the functions and mechanisms of glycosylation in cancers. Along with progress in genomics and proteomics, new findings in the significance of these complex carbohydrates, through the regulation of cell signals, have been elucidated in a wide variety of biological events. This volume provides a comprehensive summary of glycosignals and their involvement in cancer, covering numerous topics such as glycosylation machineries, regulation of phenotypes, cell signaling, immune regulation, complex carbohydrate organization, and clinical applications. The contents have been organized to promote ready understanding, covering basic to clinical research and studies on micromolecules, to animal/human cells and tissues. This book is an essential read for students and young researchers interested in cancers and carbohydrates. Specialists in glycobiology will also benefit from the new results and approaches detailed here, which provide insights into future directions of functional studies of sugar chains in both basic and applied research.
000753513 588__ $$aOnline resource; title from PDF title page (viewed January 29, 2016).
000753513 650_0 $$aCancer$$xMolecular aspects.
000753513 650_0 $$aGlycomics.
000753513 7001_ $$aFurukawa, Kōichi,$$cProfessor,$$eeditor.
000753513 7001_ $$aFukuda, Minoru,$$d1945-$$eeditor.
000753513 77608 $$iPrint version:$$z9784431559375
000753513 852__ $$bebk
000753513 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-4-431-55939-9$$zOnline Access$$91397441.1
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