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000754126 019__ $$a944186070$$a951973057
000754126 020__ $$a9783319278834$$q(electronic book)
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000754126 0247_ $$a10.1007/978-3-319-27883-4$$2doi
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000754126 049__ $$aISEA
000754126 050_4 $$aRM315
000754126 08204 $$a615.7/88$$223
000754126 24500 $$aApplied clinical pharmacokinetics and pharmacodynamics of psychopharmacological agents$$h[electronic resource] /$$cMichael W. Jann, Scott R. Penzak, Lawrence J. Cohen, editors.
000754126 264_1 $$aCham :$$bAdis,$$c2016.
000754126 300__ $$a1 online resource (xiv, 601 pages) :$$billustrations.
000754126 336__ $$atext$$btxt$$2rdacontent
000754126 337__ $$acomputer$$bc$$2rdamedia
000754126 338__ $$aonline resource$$bcr$$2rdacarrier
000754126 504__ $$aIncludes bibliographical references.
000754126 5050_ $$aSection 1. General Pharmacokinetic and Pharmacodynamic Principles of Psychopharmacological Agents -- 1. Pharmacokinetic Properties -- 2. Pharmacodynamic Properties -- 3. PET Scan and Other Biomarkers -- 4. Population Pharmacokinetics -- 5. Drug Transporters (esp. Blood Brain Barrier) -- 6. Pharmacogenomics -- Section 2. Clinical Pharmacokinetics and Pharmacodynamics of Psychopharmacological Drug Classes -- 7. Antipsychotics -- oral typical agents, oral atypical agents, and long-acting injectable (LAI) antipsychotics -- 8. Mood Stabilizers -- 9. Antidepressants -- tricyclics, selective serotonergic reuptake inhibitors, serotonergic noradrenergic reuptake inhibitors, monoamine oxidase inhibitors, and other antidepressants -- 10. Benzodiazepines and Other Sedative Hypnotics/Anxiolytics -- 11. Opioid Analgesics -- 12. Stimulants and Other Non-Stimulants for ADHD -- 13. Cholinesterase Inhibitors and Other Antidementa Agents -- 14. Anti-Addiction Agents -- 15. Anesthetics -- Section 3. Clinically Significant Drug Interactions With Psychopharmacological Agents -- 16. Antipsychotics -- 17. Mood Stabilizers -- 18. Antidepressants -- 19. Benzodiazepines and Other Sedative Hypnotics/Anxiolytics -- 20. Opioid Analgesics -- 21. Stimulants and Other Non-Stimulants for ADHD -- 22. Cholinesterase Inhibitors and Other Antidementa Agents -- 23. Anti-Addiction Agents -- 24. Anesthetics.
000754126 506__ $$aAccess limited to authorized users.
000754126 520__ $$aThis book is a comprehensive resource on psychotropic medications, detailing the latest methods for defining their characteristics, their use in different patient populations, and drug-drug interactions; an important collection of information forclinicians, students, researchers, and members of the pharmaceutical industry alike. The first section provides the foundational principles of these drugs. Mathematical modeling of parameters that affect their entryto,and exit from, the central nervous system (CNS) compartment are presented on an individual basis and then applied to target populations with specific disease states. Methods and characteristics that inform the transfer of these drugs from the laboratory bench to use in patient care are discussed, including imaging techniques, genetics and physiological barriers, such as the blood-brain barrier. The second section describes the characteristics of specific agents,nominally arranged intodifferent therapeutic categories and with reference crossover use in different disease states. The pharmacologic characteristics of different drug formulations are explored in the context of their ability to improve patient adherence. The third section focuses on drug-drug interactions.Psychotropic medications from different categories are frequently prescribed together,or alongside medications used to treat comorbid conditions, and the information provided is directly relevant to the clinic, as a result. The clinical application of pharmacokinetics and pharmacodynamics of CNS agents has made significant progress over the past 50 years and new information is reported by numerous publications in psychiatry, neurology, and pharmacology.Our understanding of the interrelationship between these medications, receptors, drug transporters, as well as techniques for measurement and monitoring their interactions,isfrequently updated. However, with information presented on a host of different platforms, and in different formats, obtaining the full picture can be difficult. This title aims to collate this information into a single source that can be easily interpreted and applied towards patient care by the clinical practitioner, and act as a reference for all others who have an interest in psychopharmacological agents.
000754126 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed March 9, 2016).
000754126 650_0 $$aPsychotropic drugs.
000754126 650_0 $$aPsychopharmacology.
000754126 650_0 $$aPharmacokinetics.
000754126 7001_ $$aJann, Michael W.,$$eeditor.
000754126 7001_ $$aPenzak, Scott R.$$eeditor.
000754126 7001_ $$aCohen, Lawrence J.$$eeditor.
000754126 77608 $$iPrint version:$$z9783319278810
000754126 852__ $$bebk
000754126 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-27883-4$$zOnline Access$$91397441.1
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000754126 980__ $$aEBOOK
000754126 980__ $$aBIB
000754126 982__ $$aEbook
000754126 983__ $$aOnline
000754126 994__ $$a92$$bISE