Immunology of the skin [electronic resource] : basic and clinical sciences in skin immune responses / Kenji Kabashima, editor.
Kabashima, Kenji, editor.
2016
RL97
Available Online

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Title
Immunology of the skin [electronic resource] : basic and clinical sciences in skin immune responses / Kenji Kabashima, editor.
ISBN
9784431558552 (electronic book)
4431558551 (electronic book)
9784431558538
DOI
https://doi.org/10.1007/978-4-431-55855-2
Published
Tokyo : Springer, 2016.
Language
English
Description
1 online resource (ix, 510 pages) : illustrations.
Item Number
10.1007/978-4-431-55855-2 doi
Call Number
RL97
Dewey Decimal Classification
616.5/079
Summary
This book reviews the role of each cell subset in the skin, providing the basics for understanding skin immunology and the mechanisms of skin diseases. The skin is one of the immune organs and is continually exposed to foreign antigens and external stimuli that must be monitored and characterized for possible elimination. Upon exposure to foreign antigens, the skin can elicit a variety of immune responses in harmony with skin components that include keratinocytes, dendritic cell subsets, mast cells, basophils, fibroblasts, macrophages, gamma-delta T cells, neutrophils, myeloid-derived suppressor cells, vascular and lymphatic cells, hair follicles, platelets, and adipose tissues, among others. In the past 10 years, knowledge of immunology has expanded drastically in areas such as innate immunity (Toll-like receptors, C-type lectins), and host defenses to bacteria and viruses, and this increased knowledge has led to the development of more effective treatment of psoriasis and other skin diseases. This book provides updates on the mechanisms of skin diseases including contact dermatitis, atopic dermatitis, psoriasis, urticaria, drug eruption, bullous diseases, anaphylaxis, graft-versus-host disease, rosacea, lymphoma, photodermatology, and collagen vascular diseases. Understanding the basics of skin immunology will help clinicians and dermatologists use new therapeutics such as biologics efficiently. Serving as an intermediary between basic science and clinical medicine, this book gives readers the opportunity to understand and marvel at the mystery and fascination of skin immunology.
Note
Includes index.
Access Note
Access limited to authorized users.
Source of Description
Online resource; title from PDF title page (SpringerLink, viewed March 14, 2016).
Added Author
Kabashima, Kenji, editor.
Available in Other Form
Print version: 9784431558538
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Preface
1 Overview: Immunology of the skin
Part 1 Components of Skin Immune Cells
2 Stratum Corneum
3 Keratinocytes
4 Langerhans cells and dermal dendritic cells
5 T cells
6 gd T cells
7 B cells
8 Mast cells and basophils
9 Neutrophil
10 Macrophages
11 Myeloid derived suppressor cells
12 Lymphatic vessels
13 Hair follicles
14 Platelets
15 Adipose tissues
Part 2 Immune Systems in the Skin
16 Innate immunity
17 C-type lectin receptors
18 Emergence of virulent Staphylococci overriding innate immunity of skin in community
19 Viral infection
20 Contact dermatitis
21 Atopic dermatitis: Common extrinsic and enigmatic intrinsic types
22 Psoriasis
23 Urticaria
24 Cutaneous adverse drug reactions: Stevens-Johnson syndrome and toxic epidermal necrolysis
25 Pemphigus
26 Anaphylaxis
27 Graft Versus Host Disease (GVHD)
28 Rosacea in skin innate immunity
29 Cutaneous Lymphomas
30 Photodermatology- Therapeutic photomedicine for skin diseases
31 Collagen vascular disease
Index.

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