000754239 000__ 02807cam\a2200445Ii\4500 000754239 001__ 754239 000754239 005__ 20230306141657.0 000754239 006__ m\\\\\o\\d\\\\\\\\ 000754239 007__ cr\cn\nnnunnun 000754239 008__ 160317s2016\\\\sz\\\\\\ob\\\\001\0\eng\d 000754239 019__ $$a945613280 000754239 020__ $$a9783319273471$$q(electronic book) 000754239 020__ $$a3319273477$$q(electronic book) 000754239 020__ $$z9783319273457 000754239 0247_ $$a10.1007/978-3-319-27347-1$$2doi 000754239 035__ $$aSP(OCoLC)ocn944961043 000754239 035__ $$aSP(OCoLC)944961043$$z(OCoLC)945613280 000754239 040__ $$aN$T$$beng$$erda$$epn$$cN$T$$dN$T$$dYDXCP$$dGW5XE$$dCDX$$dAZU$$dOCLCF$$dCOO$$dEBLCP 000754239 049__ $$aISEA 000754239 050_4 $$aRM301.28$$b.C545 2016 000754239 08204 $$a615.1$$223 000754239 24500 $$aClinical pharmacology$$h[electronic resource] :$$bcurrent topics and case studies /$$cedited by Markus Müller. 000754239 250__ $$aSecond edition. 000754239 264_1 $$aCham :$$bSpringer,$$c2016. 000754239 300__ $$a1 online resource 000754239 336__ $$atext$$btxt$$2rdacontent 000754239 337__ $$acomputer$$bc$$2rdamedia 000754239 338__ $$aonline resource$$bcr$$2rdacarrier 000754239 504__ $$aIncludes bibliographical references and index. 000754239 5050_ $$aThe discipline of Clinical Pharmacology -- Current issues in drug development -- Current issues in drug regulation -- Current issues in drug reimbursement -- Ethics of clinical research -- GCP, Scientific misconduct -- Phases of drug development, first in man studies -- Clinical trials -- Interventional studies -- Clinical trials -- observational studies -- Imaging -- Microdosing -- Genomics -- Pharmacokinetics/Pharmacodynamics -- Epidemiology, statistics -- Placebo effects -- Pharmaceutical drug safety -- Drug interactions -- Advanced therapies -- Biological pharmaceuticals -- Generic drugs, Enantiomers -- Special situations I: orphan drugs -- Special situations II: sex differences -- Special situations III: children. 000754239 506__ $$aAccess limited to authorized users. 000754239 520__ $$aThis revised and extended second edition focuses on current and emerging topics in drug development, their molecular mechanisms of action as well as regulatory issues. In addition, in-depth insights into clinical drug research and trial methodology are presented on the basis of concrete case studies. This updated book makes a valuable contribution to the field of Clinical Pharmacology and serves as a must-have guide for professors, researchers and advanced students from academia and pharmaceutical industry. . 000754239 588__ $$aOnline resource; title from PDF title page (viewed March 18, 2016) 000754239 650_0 $$aClinical pharmacology. 000754239 7001_ $$aMüller, Markus,$$eeditor. 000754239 77608 $$iPrint version:$$z9783319273457 000754239 852__ $$bebk 000754239 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-27347-1$$zOnline Access$$91397441.1 000754239 909CO $$ooai:library.usi.edu:754239$$pGLOBAL_SET 000754239 980__ $$aEBOOK 000754239 980__ $$aBIB 000754239 982__ $$aEbook 000754239 983__ $$aOnline 000754239 994__ $$a92$$bISE