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Microsystems for enhanced control of cell behavior [electronic resource] : fundamentals, design and manufacturing strategies, applications and challenges / Andrés Díaz Lantada, editor.

Lantada, Andrés Díaz, editor.
2016
R856.3
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Title
Microsystems for enhanced control of cell behavior [electronic resource] : fundamentals, design and manufacturing strategies, applications and challenges / Andrés Díaz Lantada, editor.
ISBN
9783319293288 (electronic book)
3319293281 (electronic book)
9783319293264
DOI
https://doi.org/10.1007/978-3-319-29328-8
Published
[Cham, Switzerland] : Springer, [2016]
Language
English
Description
1 online resource.
Item Number
10.1007/978-3-319-29328-8 doi
Call Number
R856.3
Dewey Decimal Classification
610.28
Summary
This handbook focuses on the entire development process of biomedical microsystems that promote special interactions with cells. Fundamentals of cell biology and mechanobiology are described as necessary preparatory input for design tasks. Advanced design, simulation, and micro/nanomanufacturing resources, whose combined use enables the development of biomedical microsystems capable of interacting at a cellular level, are covered in depth. A detailed series of chapters is then devoted to applications based on microsystems that offer enhanced cellular control, including microfluidic devices for diagnosis and therapy, cell-based sensors and actuators (smart biodevices), microstructured prostheses for improvement of biocompatibility, microstructured and microtextured cell culture matrices for promotion of cell growth and differentiation, electrophoretic microsystems for study of cell mechanics, microstructured and microtextured biodevices for study of cell adhesion and dynamics, and biomimetic microsystems (including organs-on-chips), among others. Challenges relating to the development of reliable in vitro biomimetic microsystems, the design and manufacture of complex geometries, and biofabrication are also discussed.
Bibliography, etc. Note
Includes bibliographical references.
Access Note
Access limited to authorized users.
Added Author
Lantada, Andrés Díaz, editor.
Series
Studies in mechanobiology, tissue engineering, and biomaterials ; 18.
Available in Other Form
Print version: 9783319293264
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Some introductory notes to cell behavior
Brief introduction to the field of biomedical microsystems
Brief introduction to bio-microsystems for interacting with cells
Common bioengineering resources for interacting with cells
Methodologies for the development of bio-microsystems
Addressing the complexity of biomaterials by biomimetic CAD
Multi-scale and multi-physical/biochemical modeling in bio-MEMS
Rapid prototyping of bio-MEMS for interacting with cells
Nanomanufacturing for biomedical MEMS
Issues linked to the mass-production of biomedical microsystems
Biomedical microsystems for disease management
Overview of microsystems for studying cell behavior under culture
Microsystems for studying cell adhesion, dynamics and and overall mechanobiology
Smart microsystems for active cell culture toward relevant tissues
Tissue engineering scaffolds for 3D cell culture
Tissue engineering scaffolds for bone repair: General aspects
Tissue engineering scaffolds for bone repair: Dental repair
Tissue engineering scaffolds for repairing soft tissues
Tissue engineering scaffolds for osteochondral repair
From labs-on-chips to microfluidic cell culture
Cell-based sensors and cell-based actuators
Towards reliable organs-on-chips and humans-on-chips
Towards effective and efficient biofabrication technologies
Project-based learning in the field of biomedical microsystems
Annexes.

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