Foreword I; Foreword II; Acknowledgements; Contents; Part I: General Introduction; Chapter 1: Introduction, Definitions and Historical Aspects; Introduction; Definitions; Historical Aspects; Ancient Civilizations; Modern Times; References; Part II: Basic Information for Cranial Osteomyelitis; Chapter 2: Epidemiology and Risk Factors; Epidemiology; Risk Factors for Skull Osteomyelitis; Direct Spread from Contiguous Sites; Postoperative or Secondary to Direct Trauma; Hematogenous Spread Secondary to Bacteremia or Fungemia; Comorbidities; References; Chapter 3: Different Pathogens Involved

Collection and Sample ProcessingPathogens in Cranial Osteomyelitis; Cranial Osteomyelitis Following Contiguous Source of Adjacent Infections; Cranial Osteomyelitis Secondary to Direct Inoculation; Cranial Osteomyelitis via Hematogenous Bloodborne Route; References; Chapter 4: Histopathologic Changes; Role of Histopathologic Examination; Macroscopic Appearance; Microscopic Study; Acute Osteomyelitis; Chronic Osteomyelitis; Specific Osteomyelitis of the Skull; Tuberculosis; Actinomycosis; Nocardia; Fungi; Hydatidosis; References; Chapter 5: Pathophysiology and Anatomical Spreads of Infection

Applied Anatomy of NeurocraniumExtracranial Structures; Cranial Bone Formations; Intracranial Spaces; Venous Communications; Development and Progression of the Disease; Virulence of the Pathogens; Patients Predisposing Causes and Comorbidities; Type and Location in the Skull Bones; Towards a New Classification; References; Part III: Diagnosis of Cranial Osteomyelitis; Chapter 6: Main Clinical Presentations; Cranial Osteomyelitis Associated with Otorhinologic Disease; Cranial Vault Osteomyelitis; Skull Base Osteomyelitis; Central Skull Base Osteomyelitis; Lateral Skull Base Osteomyelitis

Cranial Osteomyelitis Associated with Operation or Head InjuryPostoperative; Head Injury; Cranial Osteomyelitis Associated with Hematogenous Spread of Infection; References; Chapter 7: Laboratory Findings; Inflammatory Parameters; Blood Cultures; Molecular Studies; Microbiological Studies; Histopathologic Studies; References; Chapter 8: Imaging Studies; Plain Radiographs; Computed Tomography-Scan; Magnetic Resonance Imaging; Neurovascular Explorations; Nuclear Medicine; Ultrasound Imaging; Electroencephalography; References; Chapter 9: Differential Diagnoses: Clinical and Imaging

Mimicking Clinical PresentationsScalp Neoplasms and Nodules; Congenital Scalp Defects; Vascular Lesions; Soft Tissue Infections; Traumatic Lesions; Imaging Pattern of Cranial Vault Lesions; Eosinophilic Granuloma; Osteoma; Meningioma; Osteosarcoma; Lipoma; Fibrous Dysplasia; Hemangioma; Epidermoid and Dermoid Cysts; Metastases; Leukemias and Lymphomas; Aneurysmal Bone Cyst; Leptomeningeal Cyst; Pseudomeningocele; Pagetś Disease; Imaging Pattern of Skull Base Lesions; Tumoral Lesions; Pseudo-tumoral Lesions; References; Part IV: Management of Cranial Osteomyelitis