Modified nucleic acids [electronic resource] / Kazuhiko Nakatani, Yitzhak Tor, editors.
Nakatani, Kazuhiko, 1959- editor.; Tor, Yitzhak, editor.
2016
QP620
Available Online

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Title
Modified nucleic acids [electronic resource] / Kazuhiko Nakatani, Yitzhak Tor, editors.
ISBN
9783319271118 (electronic book)
3319271113 (electronic book)
9783319271095
DOI
https://doi.org/10.1007/978-3-319-27111-8
Published
Switzerland : Springer, 2016.
Language
English
Description
1 online resource (x, 276 pages) : illustrations.
Item Number
10.1007/978-3-319-27111-8 doi
Call Number
QP620
Dewey Decimal Classification
572.8
Summary
This book spans diverse aspects of modified nucleic acids, from chemical synthesis and spectroscopy to in vivo applications, and highlights studies on chemical modifications of the backbone and nucleobases. Topics discussed include fluorescent pyrimidine and purine analogs, enzymatic approaches to the preparation of modified nucleic acids, emission and electron paramagnetic resonance (EPR) spectroscopy for studying nucleic acid structure and dynamics, non-covalent binding of low- and high-MW ligands to nucleic acids and the design of unnatural base pairs. This unique book addresses new developments and is designed for graduate level and professional research purposes.
Note
Includes index.
Access Note
Access limited to authorized users.
Source of Description
Online resource; title from PDF title page (SpringerLink, viewed April 12, 2016).
Added Author
Nakatani, Kazuhiko, 1959- editor.
Tor, Yitzhak, editor.
Series
Nucleic acids and molecular biology ; v. 31.
Available in Other Form
Print version: 9783319271095
Linked Resources
Online Access
Record Appears in
Online Resources > Ebooks
All Resources
Emissive 5-Substituted Uridine Analogues
Fluorescent purine nucleosides and their applications
Thiazole orange-tethered nucleic acids and ECHO probes for fluorometric detection of nucleic acids
Synthetic wavelength-shifting fluorescent probes of nucleic acids
DNA Assisted Multichromophore Assembly
Polymerase Synthesis of Base-Modified DNA
Photo-cross-linking Reaction in Nucleic Acids
Chemistry and Applications
Site-Directed Spin Labeling for EPR Studies of Nucleic Acids
Non-Covalent Modification of Double Stranded DNA at the Mismatch and Bulged Site
2',4'-Bridged Nucleic Acids for Targeting Double-Stranded DNA
Specific Recognition of Single Nucleotide by Alkylating Oligonucleotides and Sensing of 8-oxoguanine
Genetic alphabet expansion by unnatural base pair creation and its application to high affinity DNA aptamers.

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