@article{755256,
      recid = {755256},
      author = {Rosado, Juan A.,},
      title = {Calcium entry pathways in non-excitable cells [electronic  resource] /},
      pages = {1 online resource (x, 471 pages) :},
      abstract = {Calcium entry pathways in non-excitable cells presents a  concise synthesis of thoughtfully selected topics covering  from the different calcium entry mechanisms in  non-excitable cells to the cellular microdomains and  organelles regulating the calcium entry process. Particular  attention is given to the fascinating group of ion channels  involved in different calcium entry pathways as well as the  emerging role of these channels in human disease. Calcium  entry is an essential mechanism for cellular function in  non-excitable cells. In general, two main calcium entry  pathways exist in non-excitable cells: one pathway, named  store-operated calcium entry (SOCE) requires store  depletion and the second pathway is regulated by receptor  occupation, but independently on calcium store depletion.  The search for the molecular components of calcium entry  has identified the stromal interaction molecule 1 (STIM1),  as the calcium sensor of the intracellular calcium stores,  and Orai as well as TRP channels as the calcium-permeable  channels located in the plasma membrane. The location,  interactions and function of these channels are finely  regulated by a number of scaffolding proteins, membrane  microdomains and cellular organelles that fine tune the  amount of calcium entering the cell. Cutting-edge and  user-friendly, this volume presents relevant background  information, critical analysis of the current observations  and directions for future research. The book is intended  for basic scientists specializing in cellular biology or  ion transport, as well as for biomedical researchers.},
      url = {http://library.usi.edu/record/755256},
}