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000755270 019__ $$a953022288
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000755270 08204 $$a579.3/23$$223
000755270 24500 $$aHelicobacter pylori research$$h[electronic resource] :$$bfrom bench to bedside /$$cSteffen Backert, Yoshio Yamaoka, editors.
000755270 264_1 $$aJapan :$$bSpringer,$$c[2016]
000755270 300__ $$a1 online resource (xi, 613 pages) :$$bcolor illustrations, maps
000755270 336__ $$atext$$btxt$$2rdacontent
000755270 337__ $$acomputer$$bc$$2rdamedia
000755270 338__ $$aonline resource$$bcr$$2rdacarrier
000755270 504__ $$aIncludes bibliographical references and index.
000755270 5050_ $$aPART 1 BACTERIOLOGY AND MOLECULAR BIOLOGY -- 1 Helicobacter pylori: genetics, recombination, population structure and human migrations -- 2 Adaptation of Helicobacter pylori metabolism to persistent gastric colonization -- 3 Virulence mechanisms of Helicobacter pylori: an overview -- 4 Roles of the cagPAI and CagA on gastroduodenal diseases -- 5 Helicobacter pylori vacuolating toxin -- 6 Roles of the BabA and the SabA adhesins in gastroduodenal diseases -- 7 Emerging novel virulence factors of Helicobacter pylori -- 8 The primary transcriptome and non-coding RNA repertoire of Helicobacter pylori -- 9 Genome evolution: Helicobacter pylori as an extreme model -- 10 Non-Helicobacter pylori Helicobacter infections in humans and animals -- PART 2 IMMUNE RESPONSES AND HOST FACTORS -- 11 Animal Models of Helicobacter pylori Infection -- 12 Helicobacter pylori and the host immune response -- 13 The role of inflammatory responses in mouse gastric tumorigenesis -- 14 Influence of host gene polymorphisms on development of gastroduodenal diseases -- PART 3 HELICOBACTER PYLORI-ASSOCIATED DISEASES -- 15 Helicobacter pylori and Nonmalignant Diseases -- 16 Helicobacter pylori and gastrointestinal polyps -- 17 Helicobacter pylori infection and gastric cancer -- 18 Helicobacter pylori infection and MALT lymphoma -- 19 Helicobacter pylori infection in children -- PART 4 TREATMENT OF HELICOBACTER PYLORI -- 20 Helicobacter pylori therapy -- 21 Management of H. pylori infection in Europe -- 22 Population-based strategies for Helicobacter pylori-associated disease management: Latin American perspective -- 23 Population-based strategies for Helicobacter pylori-associated disease management: Asian perspective -- 24 Probiotics as an alternative therapy for Helicobacter pylori-associated diseases -- 25 Vaccination against Helicobacter pylori infection.
000755270 506__ $$aAccess limited to authorized users.
000755270 520__ $$aThis book provides the current updated knowledge on all essential aspects in the rapidly evolving area of Helicobacter pylori research. H. pylori is a class I carcinogen and one of the most common infections in the world. While most people colonized by H. pylori will remain asymptomatic, up to 20 % of them may develop serious gastroduodenal disease such as peptic ulcers or gastric cancer. H. pylori is the only known bacterium linked to the development of cancer and consequently is an important focus of research. Outstanding international experts from diverse scientific disciplines contribute here to give detailed insights into the current understanding concerning the physiology and role of this pathogen. Both basic science and clinical research with actual practical consequences are taken into account. The chapters target microbiology, epidemiology, genetics, biochemistry, interactions with the immune system, signal transduction, pathogenic mechanisms in the gastroduodenal mucosa, gastric disease development, and therapy including antibiotics or probiotics treatment as well as vaccination strategies. This book is an important reference not only for clinicians but also microbiologists. It provides in a single volume an up-to-date summary of our current knowledge of this microbe and the multiple ways in which it impacts upon public health in all parts of the world.
000755270 588__ $$aOnline resource; title from PDF title page (viewed May 16, 2016).
000755270 650_0 $$aHelicobacter pylori.
000755270 650_0 $$aHelicobacter pylori infections.
000755270 7001_ $$aBackert, Steffen,$$eeditor.
000755270 7001_ $$aYamaoka, Yoshio,$$eeditor.
000755270 77608 $$iPrint version:$$tHelicobacter pylori research : from bench to bedside.$$d[Tokyo], Japan : Springer, c2016$$z9784431559344$$w(DLC) 2016935851
000755270 852__ $$bebk
000755270 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-4-431-55936-8$$zOnline Access$$91397441.1
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000755270 980__ $$aBIB
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000755270 983__ $$aOnline
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