Cancer and zebrafish [electronic resource] : mechanisms, techniques, and models / David M. Langenau, editor.
Langenau, David M., editor.
2016
RC267
Available Online

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Title Cancer and zebrafish [electronic resource] : mechanisms, techniques, and models / David M. Langenau, editor.
ISBN 9783319306544 (electronic book)
3319306545 (electronic book)
9783319306520
Published Switzerland : Springer, 2016.
Language English
Description 1 online resource (xii, 552 pages) : color illustrations.
Call Number RC267
Dewey Decimal Classification 616.99/4027
Summary This volume focuses on defining the unique attributes of using the zebrafish cancer model for discovering important pathways and potential drug targets for the treatment of human cancers. Using the zebrafish model, the volume explores oncogene and tumor suppressor discovery, chemical genetic approaches, genomics, epigenetics, cancer imaging, and cell transplantation. Contributed chapters come from the most prominent laboratories working in this field, which provides a unique perspective on zebrafish models from a wide spectrum of the research community. In addition, the book offers a detailed analysis of the most current research in the area for specific zebrafish cancer models, including T cell leukemia, rhabdomyosarcoma, liver and pancreatic cancer, melanoma, neuroblastoma, germ cell tumors, and malignant peripheral sheath tumors. A chapter is also dedicated to the development and utilization of other piscine models of cancer. The compilation of chapters in the volume culminates into a comprehensive and definitive text on zebrafish and cancer, providing a much needed resource on the powerful attributes of the zebrafish model system.
Bibliography, etc. Note Includes bibliographical references.
Access Note Access limited to authorized users.
Source of Description Online resource; title from PDF title page (SpringerLink, viewed May 18, 2016).
Added Author Langenau, David M., editor.
Series Advances in experimental medicine and biology ; v. 916.
Available in Other Form Cancer and Zebrafish : Mechanisms, Techniques, and Models.
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Record Appears in Online Resources > Ebooks
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Part 1. Powers Of The Zebrafish Model
1. Uncharted Waters: Zebrafish Cancer Models Navigate A Course for Oncogene Discovery
2. The Toolbox for Conditional Zebrafish Cancer Models
3. Approaches to Inactivate Genes in Zebrafish
4. Tumor Suppressors in Zebrafish: From Tp53 To Pten and Beyond
5. Identifying Novel Cancer Therapies Using Chemical Genetics and Zebrafish
6. Genomic Approaches To Zebrafish Cancer
7. Transcriptomic Analyses in Zebrafish Cancer Models for Global Gene Expression and Pathway Discovery
8. Zebrafish Discoveries in Cancer Epigenetics
9. Lymphatics, Cancer and Zebrafish
10. In Vivo Imaging of Cancer in Zebrafish
11. Imaging Cancer Angiogenesis and Metastasis in A Zebrafish Embryo Model
12. Allograft Cancer Cell Transplantation in Zebrafish
13. The Zebrafish Xenograft Platform: Evolution of A Novel Cancer Model and Preclinical Screening Tool
14. Automation of Technology for Cancer Research
Part 2. Cancer Models in Fish
15. Zebrafish Models Of Human Leukemia: Technological Advances and Mechanistic Insights
16. Zebrafish Rhabdomyosarcoma
17. Baiting for Cancer: Using The Zebrafish as A Model in Liver And Pancreatic Cancer
18. How Zebrafish Are Helping Us To Target Colorectal Cancer
19. Zebrafish Melanoma
20. Neuroblastoma and Its Zebrafish Model
21. Zebrafish Germ Cell Tumors
22. Malignant Peripheral Nerve Sheath Tumors
23. Xiphophorus and Medaka Cancer Models.

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