Preface; Contents; Contributors; Chapter 1: Finding and Appraising the Evidence: EBM and GRADE; Introduction; Ask the Clinical Question; Find the Evidence; Appraise the Studies; The GRADE System; The Header; Sub Heading; Outcomes; Justification for Quality Assessment; Study Limitation; Inconsistency; Directness; Precision; Publication Bias; Features Increasing Quality of Observational Studies; Large Magnitude of Effect; Dose Response Gradient; All Plausible Confounding Would Reduce the Demonstrated Effect or Increase it if No Effect Was Observed ; Summary of Findings

Other ResourcesReferences; Chapter 2: Is Surgery Indicated for Asymptomatic Giant Hepatic Hemangioma?; Introduction; Search Strategy; Results; Resection Versus Observation for Giant Hemangiomas; Treatment of Giant Hemangiomas: Operative Approaches and Non-surgical Therapies; Recommendations; A Personal View of the Data; Recommendations; References; Chapter 3: What Is the Best Surgical Method of Addressing Hepatic Hemangiomas?; Introduction; Search Strategy; Results; Observation vs Surgical Treatment with Hepatectomy; Enucleation vs Hepatectomy; Minimal Invasive Approach

RecommendationsReferences; Chapter 4: Which Diagnostic Modality is best to Assess Benign Hepatic Tumors?; Introduction; Cavernous Hemangioma; Strategy for Difficult Cases; Focal Nodular Hyperplasia; Strategy for Difficult Cases; Hepatocellular Adenoma; Strategy for Difficult Cases; Biliary Hamartoma; Conclusion; References; Chapter 5: Cystic Diseases of the Liver; Introduction; Surgical Considerations; Congenital Cysts; Neoplastic Cysts; Traumatic Cysts; Infectious Cysts; Summary; References; Chapter 6: When Should You Operate on Major Hepatic Trauma?; Introduction

Search Strategy Results; Non-operative Management; Angiography and Embolization; Outcomes; Surgical Strategies; Recommendations; A Personal View of the Data; Recommendations; References; Chapter 7: Surgical Treatment of Hepatocellular Carcinoma: Resection Versus Transplantation; Introduction; Search Strategy; Results; Resection of Hepatocellular Carcinoma; Transplantation for Hepatocellular Carcinoma; Expanding the Milan Criteria; Salvage Transplantation; Treatment Prior to Transplantation; Living Donor Liver Transplantation for HCC

Comparative Outcomes Between Resection and Transplantation for HCC Recommendations; A Personal View of the Data; References; Chapter 8: Hepatic Epithelioid Hemangioendothelioma; Introduction; Presentation; Diagnosis; Treatment; Alternative Therapies; Summary; References; Chapter 9: What Is the Best Way to Screen Cirrhotic Patients for Hepatocellular Carcinoma in the United States?; Introduction; Search Strategy; Results; Clinical Relevance and Risk Factors of Hepatocellular Carcinoma; Screening Strategies; Serum Alpha-Feto Protein (AFP)