Mechanism of functional expression of the molecular machines [electronic resource] / Masahiro Kinoshita.

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Mechanism of functional expression of the molecular machines [electronic resource] / Masahiro Kinoshita.

9789811014864 (electronic book)
9811014868 (electronic book)
9789811014840

Singapore : Springer, 2016.

English

1 online resource (x, 70 pages) : illustrations.

QP517.M65

541/.394

This brief discusses the mechanism of functional expression of a protein or protein complex utilizing the ATP hydrolysis cycle or proton-motive force from a unique point of view focused on the roles of water. A variety of processes are considered such as the unidirectional movement of a linear-motor protein along a filament, insertion of an unfolded protein into a chaperonin and release of the folded protein from it, transport of diverse substrates across the membrane by a transporter, and directed rotation of the central subunit within a rotatory motor protein complex. These topics are discussed in a unified manner within the same theoretical framework. The author argues that water plays imperative roles in the functional expression of these molecular machines. A pivotal factor is the entropic force or potential originating from the translational displacement of water molecules coexisting with the molecular machines in the entire system.

Includes bibliographical references.

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Online resource; title from PDF title page (SpringerLink, viewed June 23, 2016).

SpringerBriefs in molecular science.

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