Helicobacter pylori [electronic resource] / Nayoung Kim, editor.
Kim, Nayoung, editor.
2016
RC840.H38
Available Online

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Title Helicobacter pylori [electronic resource] / Nayoung Kim, editor.
ISBN 9789812877062 (electronic book)
9812877061 (electronic book)
9789812877055
DOI https://doi.org/10.1007/978-981-287-706-2
Published Singapore : Springer, 2016.
Language English
Description 1 online resource (x, 556 pages) : illustrations.
Other Standard Identifiers 10.1007/978-981-287-706-2 doi
Call Number RC840.H38
Dewey Decimal Classification 616.3/3014
Summary This book presents the current state of knowledge regarding the ability of Helicobacter pylori to colonize the gastrointestinal tract, the global epidemiology of H. pylori infection, transmission routes, the pathophysiology of H. pylori-related gastroduodenal and other diseases, diagnosis and treatment methods, guidelines for eradication, antibiotic resistance, the reinfection rate after H. pylori eradication, and animal models of H. pylori or related Helicobacter infection. The aim is to equip readers around the world with the understanding required in order to implement effective methods of H. pylori eradication and to enhance clinical outcomes for patients. The text is clearly written and is complemented by many helpful illustrations. This book will be a great asset in clinical practice for all practitioners who are involved in caring for patients with H. pylori-related diseases or have an interest in the subject. It will also be a useful source of information for medical students and for intelligent laypeople seeking information on H. pylori.
Note Includes index.
Access Note Access limited to authorized users.
Source of Description Online resource; title from PDF title page (SpringerLink, viewed June 23, 2016).
Added Author Kim, Nayoung, editor.
Available in Other Form Print version: 9789812877055
Linked Resources Online Access
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Part 1. Epidemiology-Prevalence and Transmission routes of H. pylori
Part 2. Pathophysiology
1) Colonization of H. pylori in the stomach
2) Brief description of Pathophysiology
3) Immune mechanism
4) Change of acid secretion, ghrelin and leptin by H. pylori
5) H. pylori virulence factors
A: toxin (CagA, VacA, DupA, OipA, IceA)
B: genetic polymorphism of toxin and disease
6) Host factors: genetic polymorphism, etc
Part 3. Diagnosis
1) Serology
2) Histology
3) Culture
4) UBT
5) Stool antigen
6) Specific conditions
A: Children
B: Bleeding
Part 4. Symptom
1)Symptom of acute and chronic H. pylori infection
Part 5. Disease
1) Atrophic gastritis and Intestinal metaplasia
2) Functional dyspepsia
3) Peptic ulcer
4) MALToma
5) Gastric cancer
A: Synopsis and Epidemiology of gastric cancer
B1: Pathogenesis: i.Genetic alternation (mutations in tumor-related genes) induced by Activation-induced cytidine deaminase (AID)
B2: Pathogenesis: ii. Epigenetic mechanisms: aberrant DNA methylation, microRNA
B3: Pathogenesis:iii. Macrophage inhibitory factor (MIF)
B4: Pathogenesis: iv. Epidermal mesenchyme transition (EMT)
B5: Pathogenesis: v. ABO blood type
B6: Pathogenesis: vi. First relatives of gastric cancer
C: H. pylori-negative gastric cancer
6) Gastroesophageal reflux disease (GERD)
7) NSAID-induced gastropathy and H. pylori infection
8) Extraintestinal manifestations of H. pylori infection
A: Iron deficiency anemia
B: Idiopathic thrombocytopenic purpura
C: Heart disease
D: Atopy and allergy
Part 6. Antibiotic resistance
1) Synopsis of antibiotic resistance
2) Clarithromycin
3) Amoxicillin
4) Quinolone
5) Metronidazole
Part 7. Treatment
1) Synopsis of antibiotic treatment
2) Triple therapy
3) Quadruple therapy
4) Sequential therapy
5) Concomitant therapy
6) Tailored therapy based on antibiotic resistance
7) Levofloxacin or rifabutin based triple therapy
8) Probiotics
9) Treatment guidelines
10) Screening method of early gastric cancer
11) Recrudescence and reinfection
Part 8. Consequences of H. pylori eradication
1) Peptic ulcer disease
2) atrophic gastritis and Intestinal metaplasia
3) Gastric cancer
Part 9. The effect of H. pylori on the other microbiota of stomach
The effect of H. pylori on the other microbiota of stomach
Part 10. Animal model- H. pylori, H. felis.

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