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000756431 020__ $$a9783319259765$$q(electronic book)
000756431 020__ $$a3319259768$$q(electronic book)
000756431 020__ $$z9783319259741
000756431 035__ $$aSP(OCoLC)ocn953662123
000756431 035__ $$aSP(OCoLC)953662123
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000756431 050_4 $$aRC931.O73
000756431 08204 $$a616.7/16$$223
000756431 08204 $$a610
000756431 24500 $$aOsteoporosis in older persons$$h[electronic resource] :$$badvances in pathophysiology and therapeutic approaches /$$cGustavo Duque, Douglas P. Kiel, editors.
000756431 250__ $$a2nd ed.
000756431 260__ $$aCham :$$bSpringer,$$c2016.
000756431 300__ $$a1 online resource (299 pages)
000756431 336__ $$atext$$btxt$$2rdacontent
000756431 337__ $$acomputer$$bc$$2rdamedia
000756431 338__ $$aonline resource$$bcr$$2rdacarrier
000756431 500__ $$aImplications for Screening
000756431 5050_ $$aAcknowledgements; Foreword; Preface; Contents; Contributors; 1: Biology of Bone; Overview; Bone Growth and Development; Bone Cell Differentiation; Osteoprogenitors, Osteoblasts, and Osteocytes; Regulators of Osteoblastic Cell Differentiation and Function; Wnt Signaling Molecules; Parathyroid Hormone; Vitamin D3; Estrogen; Bone Morphogenetic Proteins; Growth Hormone/Insulin-Like Growth Factor; Leptin/[beta] Adrenergic Receptors; Glucocorticoids; Thyroid Hormone; MicroRNAs; Monocytes/Macrophages and Osteoclastogenesis; Modulators of Osteoclastic Cell Differentiation and Function
000756431 5058_ $$aBone Turnover Measurement of Bone Turnover; Bone Formation Markers; Bone Resorption Markers; Bone Turnover and Aging; Role of Bone and Bone Cells in Stem Cell Biology; References; 2: Aging and Bone; Introduction; Aging: A Definition; Contribution of Telomere Shortening to Age-Related Osteoblast Dysfunction; Other Aspects of Cellular Senescence; Aging and Bone Physiology; Skeletal Stem Cell (Also Known as Bone Marrow Stromal or Mesenchymal Stem Cells) (BMSC); The Inverse Relationship Between Adipocytes and Osteoblasts
000756431 5058_ $$aBiochemical Signaling Pathways, Genetic and Pharmaceutical Targets in Aging Why Fat?; Which Fat?; What Makes It Bone vs. Fat?; Apoptosis and the Aging Bone; References; 3: Calciotropic Hormones; Calcium; Vitamin D; Parathyroid Hormone; Calcitonin; Summary/Conclusion; References; 4: The Muscle-Bone Connection; Mechanical Coupling of Bones and Muscles; Beyond Mechanical Coupling: Bone-Muscle Developmental and Genetic Coupling; Genome Wide Association Studies (GWAS); Disease Conditions with Multiple Tissue Effects; The Unique Case of Fracture Healing
000756431 5058_ $$aBones and Muscles as Endocrine Organs Bone as an Endocrine Organ; Muscle as an Endocrine Organ; Interplay Between Bones and Muscles as Endocrine Organs; Musculoskeletal Diseases: The Special Cases of Osteoporosis and Sarcopenia; Osteoporosis; Sarcopenia; The Role of Cartilage, Ligaments, and Tendons in Bone-Muscle Crosstalk; Crosstalk in MSK Development; Bone-Cartilage Crosstalk; Tendon-Muscle Crosstalk; Concluding Remarks and Future Directions; References; 5: Sex Steroids and Aging Bone; Introduction; Methodologic Issues; Sex Steroids and Age
000756431 5058_ $$aSex Steroids and Bone Mineral Density (BMD) Women; Men; Sex Steroids, Volumetric BMD and Skeletal Structure; Sex Steroids and Fractures; Women; Men; Summary; References; 6: Animal Models for Aging Bone; Introduction; Normally Aged Animal Models; Genetic Manipulation and Accelerated Aging; Osteopenia Caused by Decrease in Bone Formation; The Aging Phenotype and Defects in Mineral Metabolism; What Mouse Models Teach; References; 7: Osteoporosis as a Geriatric Syndrome; Introduction; What is a Geriatric Syndrome?; The Case for Osteoporotic Fractures as a Geriatric Syndrome
000756431 506__ $$aAccess limited to authorized users.
000756431 520__ $$aThis second edition brings together the latest information about the pathophysiology and new therapeutic alternatives for osteoporosis of advanced age. Written by highly recognised clinicians and basic scientists in the field of aging bone research, this book includes aspects of muscle and bone interaction focusing on the impact of age-related muscle loss (sarcopenia) on the pathogenesis of falls and fractures in older persons. Osteoporosis in Older Persons- Advances in Pathophysiology and Therapeutic Approach, Second Edition, aids the reader in understanding the mechanisms of senile osteoporosis with a practical approach to the treatment of its consequences. It is the perfect reference guide for geriatricians, gerontologists and bone biologists, as well as medical trainees. .
000756431 588__ $$aDescription based on print version record.
000756431 650_0 $$aOsteoporosis.
000756431 7001_ $$aDuque, Gustavo.
000756431 7001_ $$aKiel, Douglas P.
000756431 77608 $$iPrint version:$$aDuque, Gustavo$$tOsteoporosis in Older Persons : Advances in Pathophysiology and Therapeutic Approaches$$dCham : Springer International Publishing,c2016$$z9783319259741
000756431 852__ $$bebk
000756431 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-25976-5$$zOnline Access$$91397441.1
000756431 909CO $$ooai:library.usi.edu:756431$$pGLOBAL_SET
000756431 980__ $$aEBOOK
000756431 980__ $$aBIB
000756431 982__ $$aEbook
000756431 983__ $$aOnline
000756431 994__ $$a92$$bISE