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000756616 020__ $$a9783319411712$$q(electronic book)
000756616 020__ $$a3319411713$$q(electronic book)
000756616 020__ $$z9783319411705
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000756616 035__ $$aSP(OCoLC)954214878
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000756616 24500 $$aInflammasome signaling and bacterial infections$$h[electronic resource] /$$cedited by Steffen Backert, editor.
000756616 264_1 $$aSwitzerland :$$bSpringer,$$c2016.
000756616 300__ $$a1 online resource (xi, 282 pages) :$$billustrations.
000756616 336__ $$atext$$btxt$$2rdacontent
000756616 337__ $$acomputer$$bc$$2rdamedia
000756616 338__ $$aonline resource$$bcr$$2rdacarrier
000756616 4901_ $$aCurrent topics in microbiology and immunology,$$x0070-217X ;$$vvolume 397
000756616 506__ $$aAccess limited to authorized users.
000756616 520__ $$aThis volume details our current understanding of the architecture and signaling capabilities of known canonical and non-canonical inflammasome complexes and highlights their action, in particular in response to infection with important bacterial model organisms and the corresponding disease pathologies. The first chapters review new insights into the assembly and structures of inflammasome components and emphasize general strategies of up- and downstream signaling events. In addition, the authors specifically discuss the composition and activity of inflammasomes during infection with various gut pathogens (Salmonella, Shigella, Yersinia, Listeria and Helicobacter), respiratory pathogens (Mycobacterium, Legionella, Burkholderia and Streptococcus) as well as skin and soft tissue pathogens (Francisella and Staphylococcus). The discoveries presented provide a better understanding of the cellular and molecular biology of inflammasomes, which will pinpoint important new therapeutic targets for the treatment and prevention of multiple infectious diseases in the future. It is a valuable resource for students, scientists and clinicians, providing up-to-date information on this emerging research topic.
000756616 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed August 3, 2016).
000756616 650_0 $$aInflammation$$xImmunological aspects.
000756616 7001_ $$aBackert, Steffen,$$eeditor.
000756616 830_0 $$aCurrent topics in microbiology and immunology ;$$vv. 397.
000756616 852__ $$bebk
000756616 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-41171-2$$zOnline Access$$91397441.1
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000756616 982__ $$aEbook
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