000759869 000__ 03613cam\a2200469Ii\4500 000759869 001__ 759869 000759869 005__ 20230306141937.0 000759869 006__ m\\\\\o\\d\\\\\\\\ 000759869 007__ cr\un\nnnunnun 000759869 008__ 160804s2016\\\\sz\a\\\\ob\\\\000\0\eng\d 000759869 020__ $$a9783319388045$$q(electronic book) 000759869 020__ $$a3319388045$$q(electronic book) 000759869 020__ $$z9783319388021 000759869 020__ $$z3319388029 000759869 0247_ $$a10.1007/978-3-319-38804-5$$2doi 000759869 035__ $$aSP(OCoLC)ocn955018660 000759869 035__ $$aSP(OCoLC)955018660 000759869 040__ $$aYDXCP$$beng$$erda$$epn$$cYDXCP$$dIDEBK$$dEBLCP$$dN$T$$dGW5XE$$dAZU$$dCOO$$dOCLCF 000759869 049__ $$aISEA 000759869 050_4 $$aQP281 000759869 08204 $$a618.3/4$$223 000759869 08204 $$a610 000759869 1001_ $$aDuttaroy, Asim K.,$$eauthor. 000759869 24510 $$aEarly nutrition and lifestyle factors$$h[electronic resource] :$$beffects on first trimester placenta /$$cAsim K. Duttaroy, Sanjay Basak. 000759869 264_1 $$aSwitzerland :$$bSpringer,$$c2016. 000759869 300__ $$a1 online resource (x, 159 pages) :$$billustrations. 000759869 336__ $$atext$$btxt$$2rdacontent 000759869 337__ $$acomputer$$bc$$2rdamedia 000759869 338__ $$aonline resource$$bcr$$2rdacarrier 000759869 504__ $$aIncludes bibliographical references. 000759869 5050_ $$a1. Growth factors, microenvironment and placentation -- 2. Major nutrients and their roles on placentation -- 3. Long chain fatty acids and their effects on placentation -- 4. Folic acid, vitamin B12 and their role on early placentation -- 5. Vitamins as early nutrient for the growth and development of the fetus -- 6. Hyperglycemia and its effect on placentation -- 7. Impact of maternal stress and smoking on placentation -- 8. Effects of maternal obesity and cytokines on placentation -- 9. Regulation of placentation by lifestyle and environmental factors -- 10. Epigenetics and placental development -- 11. Expression of genes responsible for placentation -- 12. Importance of Docosahexaenoic acid on placentation processes -- 13. Sources of key nutrients for successful placentation -- 14. Placentation as a predictor of feto-placental outcome. . 000759869 506__ $$aAccess limited to authorized users. 000759869 520__ $$aThis book highlights the impact of nutrients on early placentation processes and their relevance for fetal growth and pregnancy outcome. The role of maternal nutrition on fetal growth and development has been evidenced in many epidemiological studies that included infamous Dutch famine, Helsinki Birth cohort and others. Fetal programming hypothesis states that the nutritional and other environmental conditions under which an individual develops from pre-conception to birth has a major impact on the future health of the newborn child. The developmental environment of the fetus is primarily dependent on two major factors that are maternal nutritional state (excess/low/imbalance) and placental function. Placentation is characterized by the extensive remodeling of the maternal uterine vasculature producing low-resistance blood vessels that facilitate the exchange of nutrients and wastes between the mother and the fetus. Cellular and molecular mechanisms involved in human placental blood vessel formation, which are now well established, are discussed. 000759869 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed August 9, 2016). 000759869 650_0 $$aPlacenta. 000759869 650_0 $$aMaternal-fetal exchange. 000759869 7001_ $$aBasak, Sanjay,$$d1971-$$eauthor. 000759869 77608 $$iPrint version:$$z9783319388021$$z3319388029$$w(OCoLC)946908026 000759869 852__ $$bebk 000759869 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-38804-5$$zOnline Access$$91397441.1 000759869 909CO $$ooai:library.usi.edu:759869$$pGLOBAL_SET 000759869 980__ $$aEBOOK 000759869 980__ $$aBIB 000759869 982__ $$aEbook 000759869 983__ $$aOnline 000759869 994__ $$a92$$bISE