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Table of Contents
Preface to the Second Edition; Contents; Contributors; Introduction: Rationale for Machine Use; Key Developments Leading to the Emergence of Machines for Neurorehabilitation; The First Robots for Rehabilitation Training; The Rationale for Machine Use in Rehabilitation Therapy; What Is Needed for a Successful Training?; References; Part I: Basic Framework: Motor Recovery, Learning, and Neural Impairment; 1: Learning in the Damaged Brain/Spinal Cord: Neuroplasticity; 1.1 Learning in the CNS; 1.2 Mechanisms of Neuroplasticity in Learning and After Lesions; 1.2.1 Gene Expression
1.2.2 Cellular Plasticity1.2.3 Systems Plasticity in the Brain; 1.2.4 Plasticity in the Spinal Cord; 1.2.4.1 Spinal Reflex Plasticity; 1.2.4.2 Task-Specific Plasticity Here; 1.2.5 Subcortical Contributions to Movement Learning; 1.3 Learning and Plasticity During Rehabilitation Therapy; 1.3.1 Lesions of Cortex and Descending Pathways; 1.3.2 Cerebellar Lesions; 1.3.3 Spinal Lesions; 1.3.3.1 Plasticity of Spinal Neuronal Circuits: Rehabilitation Issues; 1.3.3.2 Functional Training in Persons with a Spinal Cord Injury; 1.3.3.3 Prerequisites for a Successful Training; Conclusion
3.3 Using Robotic Technologies to Provide Challenge in Rehabilitation Therapy3.3.1 Providing Appropriate Challenge by Providing Mechanical Assistance; 3.3.2 Adapting Challenge; 3.3.3 Implication of Challenge on Motivation and Self-Efficacy; 3.4 Expanding Options for Patient Challenge with Rehabilitation Robotics: The KineAssistTM-Mobility eXtreme as a Case Study; 3.4.1 Introducing Challenge During Balance and Walking Training Poststroke; Conclusion; References; 4: Multisystem Neurorehabilitation in Rodents with Spinal Cord Injury; 4.1 Introduction
4.2 Experimental Concepts Underlying ℗ƯActivity-℗ƯDependent Plasticity After a SCI4.3 Motor Control-Enabling Systems After a SCI; 4.3.1 Electrically Enabled Motor Control (eEMC); 4.3.2 Pharmacologically Enabled Motor Control (fEMC); 4.3.3 Robotically Enabled Motor Control (rEMC); 4.3.4 Sensory-Enabled Motor Control (sEMC); 4.4 Impact of Chronic SCI on the Function of Spinal Circuitries; 4.5 Neurorehabilitation with Motor Control-Enabling Systems; 4.6 Development of Operative Neuroprosthetic Systems; 4.7 Perspectives for Viable Clinical Applications; Conclusions; References
1.2.2 Cellular Plasticity1.2.3 Systems Plasticity in the Brain; 1.2.4 Plasticity in the Spinal Cord; 1.2.4.1 Spinal Reflex Plasticity; 1.2.4.2 Task-Specific Plasticity Here; 1.2.5 Subcortical Contributions to Movement Learning; 1.3 Learning and Plasticity During Rehabilitation Therapy; 1.3.1 Lesions of Cortex and Descending Pathways; 1.3.2 Cerebellar Lesions; 1.3.3 Spinal Lesions; 1.3.3.1 Plasticity of Spinal Neuronal Circuits: Rehabilitation Issues; 1.3.3.2 Functional Training in Persons with a Spinal Cord Injury; 1.3.3.3 Prerequisites for a Successful Training; Conclusion
3.3 Using Robotic Technologies to Provide Challenge in Rehabilitation Therapy3.3.1 Providing Appropriate Challenge by Providing Mechanical Assistance; 3.3.2 Adapting Challenge; 3.3.3 Implication of Challenge on Motivation and Self-Efficacy; 3.4 Expanding Options for Patient Challenge with Rehabilitation Robotics: The KineAssistTM-Mobility eXtreme as a Case Study; 3.4.1 Introducing Challenge During Balance and Walking Training Poststroke; Conclusion; References; 4: Multisystem Neurorehabilitation in Rodents with Spinal Cord Injury; 4.1 Introduction
4.2 Experimental Concepts Underlying ℗ƯActivity-℗ƯDependent Plasticity After a SCI4.3 Motor Control-Enabling Systems After a SCI; 4.3.1 Electrically Enabled Motor Control (eEMC); 4.3.2 Pharmacologically Enabled Motor Control (fEMC); 4.3.3 Robotically Enabled Motor Control (rEMC); 4.3.4 Sensory-Enabled Motor Control (sEMC); 4.4 Impact of Chronic SCI on the Function of Spinal Circuitries; 4.5 Neurorehabilitation with Motor Control-Enabling Systems; 4.6 Development of Operative Neuroprosthetic Systems; 4.7 Perspectives for Viable Clinical Applications; Conclusions; References