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Preface; Extracellular Composite Matrices inßArthropods; Contents; Contributors; Part I: Skeletal Matrices; Chapter 1: Genes ofßCuticular Proteins andßTheir Regulation; 1.1 Recent Classification ofßCuticular Proteins andßtheßConstruction ofßCuticular Layers; 1.1.1 Recent Classification ofßCuticular Proteins; 1.1.2 The Construction ofßCuticular Layers; 1.1.3 Distinctive Function ofßEach Cuticular Protein; 1.2 Factors that Affect Gene Expression ofßCuticular Proteins; 1.2.1 Ecdysone; 1.2.2 Ecdysone Signaling Cascade; 1.2.3 Target Genes ofßEcdysone-Responsive Transcription Factors.

1.2.4 Remodeling ofßChromatin andßHistone Modification1.2.5 Juvenile Hormone; 1.3 Application ofßGenome Information; 1.3.1 Recent Genomic Research, Annotation andßAnalysis ofßCuticular Protein Genes; 1.3.2 Clustering ofßCuticular Protein Genes; 1.3.3 Analysis ofßtheßBinding Sites ofßTranscription Factors; 1.3.4 Application ofßGenomic Information vis-á-vis theßCuticular Protein Research; 1.3.4.1 Genomic Research andßExpression Profiles ofßCuticular Protein Genes; 1.3.5 Genomic Research ofßtheßRegulatory Region ofßCuticular Protein Genes; 1.4 Regulation ofßGene Expression ofßCuticular Proteins.

1.4.1 Cuticular Protein Genes inßLarval Integument DuringßMolting1.4.2 Cuticular Protein Genes inßtheßIntermolt Stage; 1.4.3 Cuticular Protein Genes inßtheßPrepupal Stage; 1.4.4 Cuticular Proteins Genes inßtheßAdult Cuticular Layer; 1.4.5 Different Regulation at Different Stages; 1.4.6 Other Factors that Affect theßExpression ofßCuticular Protein Genes; 1.5 Future Prospects; References; Chapter 2: Chitin Metabolic Pathways inßInsects andßTheir Regulation; 2.1 Introduction; 2.2 Structure ofßChitin; 2.3 Higher Order Structures Involving Chitin Fibers inßtheßCuticle.

2.4 Higher Order Structure inßtheßPeritrophic Matrix2.5 Precursors ofßChitin andßGeneration ofßActivated Substrates; 2.6 Towards theßMode ofßAction ofßInsect Chitin Synthases; 2.7 Regulation ofßChitin Synthesis; 2.8 Chitin Deacetylation andßPossible Role inßCuticle Assembly; 2.9 Chitin Deacetylases inßInsects; 2.10 Chitin Degradation; 2.10.1 Chitinases Are Encoded byßaßVery Large Family ofßGenes; 2.10.2 Domain Organization andßStructure ofßChitinases; 2.10.3 Tissue Specificity andßRegulation ofßExpression ofßChitinase Families; 2.10.4 Specialization inßtheßFunctions ofßFamilies ofßChitinases.

2.11 Chitinolytic N-Acetylglucosaminidases (EC 3.2.1.52) andßTheir Genes2.12 Additional Proteins Involved inßChitin Protection andßDegradation; 2.13 Cuticular Proteins Analogous toßPeritrophins (CPAPs); 2.14 Cuticular Proteins Belonging toßR & R andßOther Groups; 2.15 Concluding Remarks; References; Chapter 3: Molecular Model ofßSkeletal Organization andßDifferentiation; 3.1 Introduction; 3.2 Cuticles ofßModel Insects; 3.2.1 The Cuticle ofßRhodnius prolixus; 3.2.2 The Cuticle ofßCalpodes ethlius; 3.2.3 The Cuticle ofßDrosophila melanogaster; 3.2.3.1 Cuticle Structure.

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