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Author Bio; Contents; Chapter 1: Nanotechnology andßIts Drug Delivery Applications; 1.1 Introduction; 1.2 Historical Prospects ofßNanotechnology; 1.3 Promising Role inßDrug Delivery; 1.3.1 Nanoparticles andßDrug Delivery; 1.3.2 Use ofßNPs Formulation inßDrug Delivery; 1.3.3 Cellular andßIntracellular Targets; 1.3.4 The Brain-The Ultimate Target forßDrug Delivery; 1.4 Innovations inßNanotechnology; 1.5 Nanotechnology Theory toßApplications; 1.6 Nanomedicine/Nanoscience/Nano-Engineering andßRelationship withßDrug Delivery; 1.6.1 Nanomedicine andßDrug Delivery.
1.6.1.1 Advantages ofßNanoparticles forßNanomedicine1.6.1.2 Challenges; 1.6.2 Nanoengineering andßDrug Delivery; 1.7 Types ofßNanodelivery: Natural or Synthetic; 1.7.1 Synthetic Polymers; 1.7.2 Natural Polymers; 1.8 Natural andßSynthetic Polymeric Nanoparticles; References; Chapter 2: Nanoparticles Types, Classification, Characterization, Fabrication Methods andßDrug Delivery Applications; 2.1 Introduction; 2.2 Classification ofßNanoparticles; 2.3 Characterization ofßNanoparticles; 2.3.1 Particle Size; 2.3.1.1 Photon-Correlation Spectroscopy (PCS) or Dynamic Light Scattering (DLS).
2.3.1.2 Scanning Electron Microscopy (SEM)2.3.1.3 Transmission Electron Microscope; 2.3.1.4 Atomic Force Microscopy; 2.3.2 Surface Charge; 2.3.3 Surface Hydrophobicity; 2.3.4 Drug Release; 2.4 Preparation ofßNanoparticles; 2.4.1 Solvent Evaporation Method; 2.4.2 Spontaneous Emulsification or Solvent Diffusion Method; 2.4.3 Double Emulsion andßEvaporation Method; 2.4.4 Salting Out Method; 2.4.4.1 Advantages; 2.4.4.2 Disadvantages; 2.4.5 Emulsions-Diffusion Method; 2.4.5.1 Disadvantages; 2.4.6 Solvent Displacement/Precipitation Method; 2.4.7 Coacervation or Ionic Gelation Method.
2.4.8 Polymerization Method2.4.9 Production ofßNanoparticles Using Supercritical Fluid Technology; 2.5 Most Favorable Requirements forßDesigning Therapeutic Nanoparticles; 2.6 Types ofßPharmaceutical Nanosystems; 2.6.1 Carbon Based Structures; 2.6.1.1 Applications; 2.6.2 Fullerenes; 2.6.2.1 Applications; 2.6.2.2 Toxicity; 2.6.3 Quantum Dots; 2.6.3.1 Applications; 2.6.3.2 Toxicity; 2.6.4 Nanoshells; 2.6.4.1 Applications; 2.6.5 Nanobubbles; 2.6.5.1 Applications; Toxicity; 2.6.6 Paramagnetic Nanoparticles; 2.6.6.1 Applications; 2.6.7 Nanosomes; 2.6.8 Pharmacyte; 2.6.8.1 Niosome.
2.6.9 Dendrimers2.6.9.1 Applications; 2.6.9.2 Toxicity; 2.6.10 Nanopores; 2.6.10.1 Application; 2.6.11 Microbivores; 2.6.11.1 Application; 2.6.12 Nanocrystals andßNanosuspension; 2.6.12.1 Applications; 2.6.12.2 Toxicity; 2.6.13 Solid Lipid Nanoparticles; 2.6.13.1 Applications; 2.6.14 Silicon-Based Structures; 2.6.14.1 Applications; 2.6.15 Metallic Nanoparticles; 2.6.15.1 Applications; 2.6.16 Liposomes; 2.6.16.1 Applications; 2.6.17 Polymeric Micelles; 2.6.18 Polymer Drug Conjugate; 2.6.19 Polyplexes/Lipopolyplexes; 2.6.20 Respirocytes; 2.6.21 Polymeric Nanoparticles.
1.6.1.1 Advantages ofßNanoparticles forßNanomedicine1.6.1.2 Challenges; 1.6.2 Nanoengineering andßDrug Delivery; 1.7 Types ofßNanodelivery: Natural or Synthetic; 1.7.1 Synthetic Polymers; 1.7.2 Natural Polymers; 1.8 Natural andßSynthetic Polymeric Nanoparticles; References; Chapter 2: Nanoparticles Types, Classification, Characterization, Fabrication Methods andßDrug Delivery Applications; 2.1 Introduction; 2.2 Classification ofßNanoparticles; 2.3 Characterization ofßNanoparticles; 2.3.1 Particle Size; 2.3.1.1 Photon-Correlation Spectroscopy (PCS) or Dynamic Light Scattering (DLS).
2.3.1.2 Scanning Electron Microscopy (SEM)2.3.1.3 Transmission Electron Microscope; 2.3.1.4 Atomic Force Microscopy; 2.3.2 Surface Charge; 2.3.3 Surface Hydrophobicity; 2.3.4 Drug Release; 2.4 Preparation ofßNanoparticles; 2.4.1 Solvent Evaporation Method; 2.4.2 Spontaneous Emulsification or Solvent Diffusion Method; 2.4.3 Double Emulsion andßEvaporation Method; 2.4.4 Salting Out Method; 2.4.4.1 Advantages; 2.4.4.2 Disadvantages; 2.4.5 Emulsions-Diffusion Method; 2.4.5.1 Disadvantages; 2.4.6 Solvent Displacement/Precipitation Method; 2.4.7 Coacervation or Ionic Gelation Method.
2.4.8 Polymerization Method2.4.9 Production ofßNanoparticles Using Supercritical Fluid Technology; 2.5 Most Favorable Requirements forßDesigning Therapeutic Nanoparticles; 2.6 Types ofßPharmaceutical Nanosystems; 2.6.1 Carbon Based Structures; 2.6.1.1 Applications; 2.6.2 Fullerenes; 2.6.2.1 Applications; 2.6.2.2 Toxicity; 2.6.3 Quantum Dots; 2.6.3.1 Applications; 2.6.3.2 Toxicity; 2.6.4 Nanoshells; 2.6.4.1 Applications; 2.6.5 Nanobubbles; 2.6.5.1 Applications; Toxicity; 2.6.6 Paramagnetic Nanoparticles; 2.6.6.1 Applications; 2.6.7 Nanosomes; 2.6.8 Pharmacyte; 2.6.8.1 Niosome.
2.6.9 Dendrimers2.6.9.1 Applications; 2.6.9.2 Toxicity; 2.6.10 Nanopores; 2.6.10.1 Application; 2.6.11 Microbivores; 2.6.11.1 Application; 2.6.12 Nanocrystals andßNanosuspension; 2.6.12.1 Applications; 2.6.12.2 Toxicity; 2.6.13 Solid Lipid Nanoparticles; 2.6.13.1 Applications; 2.6.14 Silicon-Based Structures; 2.6.14.1 Applications; 2.6.15 Metallic Nanoparticles; 2.6.15.1 Applications; 2.6.16 Liposomes; 2.6.16.1 Applications; 2.6.17 Polymeric Micelles; 2.6.18 Polymer Drug Conjugate; 2.6.19 Polyplexes/Lipopolyplexes; 2.6.20 Respirocytes; 2.6.21 Polymeric Nanoparticles.