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000761571 019__ $$a959329373$$a959609426
000761571 020__ $$a9783319339139$$q(electronic book)
000761571 020__ $$a3319339133$$q(electronic book)
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000761571 08204 $$a615.78
000761571 24500 $$aTranslational neuropsychopharmacology /$$cTrevor W. Robbins, Barbara J. Sahakian, editors.
000761571 260__ $$aSwitzerland :$$bSpringer,$$cc2016.
000761571 300__ $$a1 online resource (503 pages)
000761571 336__ $$atext$$btxt$$2rdacontent
000761571 337__ $$acomputer$$bc$$2rdamedia
000761571 338__ $$aonline resource$$bcr$$2rdacarrier
000761571 4901_ $$aCurrent Topics in Behavioral Neurosciences ;$$vv. 28
000761571 500__ $$a5010 On the Road to Translation for PTSD Treatment: Theoretical and Practical Considerations of the Use of Human Models of Conditioned Fear for Drug Development
000761571 5050_ $$aPreface; Contents; 5003 Translational Mouse Models of Autism: Advancing Toward Pharmacological Therapeutics; Abstract; 1 Introduction; 2 Animal Models to Understand the Causes of Autism; 3 Mouse Behavioral Assays Relevant to the Diagnostic and Associated Symptoms of Autism; 3.1 Social Tests; 3.2 Social Communication; 3.3 Motor Stereotypies, Repetitive Behaviors, and Restricted Interests; 3.4 Associated Symptoms; 4 Evaluating Pharmacological Therapeutics in Animal Models with High Construct Validity and Strong Face Validity for ASD; 5 Conclusions; Acknowledgments; References
000761571 5058_ $$a5013 Translatable and Back-Translatable Measurement of Impulsivity and Compulsivity: Convergent and Divergent ProcessesAbstract; 1 Introduction; 2 Impulsivity; 2.1 Waiting Impulsivity; 2.1.1 Neural Networks and Neurochemistry; 2.2 Stop-Signal Reaction Time; 2.2.1 Neural Substrates; 2.3 Delay Discounting; 2.3.1 Neural Substrates; 2.4 Reflection Impulsivity; 2.4.1 Neural Substrates; 3 Compulsivity; 3.1 Cognitive Inflexibility; 3.1.1 Neural Substrates; 3.2 Stimulus-Response (Habit) Learning; 3.2.1 Neural Substrates; 3.3 Motor Stereotypy; 4 Synthesis and Future Perspectives
000761571 5058_ $$a4.1 Neural Considerations: Fronto-striatal Nodes and Opponency Processes4.2 Neurochemical Considerations: Dopamine and Serotonin; 5 Conclusion; Acknowledgements; References; 5014 Translational Models of Gambling-Related Decision Making; Abstract; 1 Introduction; 1.1 The Iowa Gambling Task; 2 Challenges to Translational Research into Gambling; 2.1 Multiple Types of Gambling; 2.2 Reliance upon Models of Drug Addiction; 2.3 The Puzzle of Dopamine and GD; 2.4 Comorbidity of GD with Other Psychiatric Conditions; 2.5 Subjective Biases in Decision-Making Under Uncertainty; 3 Escalation of Commitment
000761571 5058_ $$a3.1 Loss-Chasing4 The Near-miss Effect; 5 Conclusion; References; 5005 Translational Research on Nicotine Dependence; Abstract; 1 Introduction and Overarching Model; 2 Role of the Endogenous Opioid System in Nicotine Reward and Relapse; 2.1 Biological Mechanisms; 2.2 Future Directions for Treatment; 3 Interactions Between Smoking and Overeating; 3.1 Post-cessation Weight Gain; 3.2 Altered Nicotine Reward in Obesity; 3.3 Future Directions for Treatment; 4 Nicotine Withdrawal: Cognition and Affect; 4.1 Withdrawal-Related Cognitive Changes; 4.2 Withdrawal-Related Affective Changes
000761571 5058_ $$a4.3 Future Directions for Treatment5 Summary and Conclusion; References; 5006 The Need for Treatment Responsive Translational Biomarkers in Alcoholism Research; Abstract; 1 Alcohol Addiction: An Area of Major Unmet Medical Needs; 2 The Aspirations of Translational Research for Alcohol Addiction; 3 The Promise of Translational Biomarkers; 3.1 Alcohol-Induced Dopamine (DA) Activation as Translational Biomarker; 3.2 Measures of Glutamate Activity as Translational Biomarkers; 4 Future Directions: The Whole-More than the Sum of Its Parts?; 5 Conclusion; References
000761571 506__ $$aAccess limited to authorized users.
000761571 588__ $$aDescription based on print version record.
000761571 650_0 $$aNeuropsychopharmacology.
000761571 7001_ $$aRobbins, Trevor W.
000761571 7001_ $$aSahakian, B. J.
000761571 77608 $$iPrint version:$$aRobbins, Trevor W.$$tTranslational Neuropsychopharmacology$$dCham : Springer International Publishing,c2016$$z9783319339115
000761571 830_0 $$aCurrent topics in behavioral neurosciences ;$$vv. 28.
000761571 852__ $$bebk
000761571 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-33913-9$$zOnline Access$$91397441.1
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