000763392 000__ 02563cam\a2200469Ii\4500 000763392 001__ 763392 000763392 005__ 20230306142308.0 000763392 006__ m\\\\\o\\d\\\\\\\\ 000763392 007__ cr\cn\nnnunnun 000763392 008__ 161014s2016\\\\sz\a\\\\o\\\\\001\0\eng\d 000763392 019__ $$a962434221 000763392 020__ $$a9783319429496$$q(electronic book) 000763392 020__ $$a3319429493$$q(electronic book) 000763392 020__ $$z9783319429472 000763392 0247_ $$a10.1007/978-3-319-42949-6$$2doi 000763392 035__ $$aSP(OCoLC)ocn960700537 000763392 035__ $$aSP(OCoLC)960700537$$z(OCoLC)962434221 000763392 040__ $$aGW5XE$$beng$$erda$$epn$$cGW5XE$$dAZU$$dIDEBK$$dYDX$$dOCLCF 000763392 049__ $$aISEA 000763392 050_4 $$aRC268.4 000763392 08204 $$a616.9/9404$$223 000763392 24500 $$aSTAT inhibitors in cancer /$$cAlister C. Ward, editor. 000763392 264_1 $$aCham, Switzerland :$$bHumana Press,$$c2016. 000763392 300__ $$a1 online resource (vii, 195 pages) :$$bcolor illustrations. 000763392 336__ $$atext$$btxt$$2rdacontent 000763392 337__ $$acomputer$$bc$$2rdamedia 000763392 338__ $$aonline resource$$bcr$$2rdacarrier 000763392 4901_ $$aCancer drug discovery and development,$$x2196-9906 000763392 500__ $$aIncludes index. 000763392 5050_ $$aSTATs in Health and Disease -- STAT Proteins in Cancer -- Translating STAT Inhibitors from the Lab to the Clinic -- Historical Development of STAT3 Inhibitors and Early Results in Clinical Trials -- STAT3 Inhibitors in Cancer: A Comprehensive Update -- Targeting Upstream Janus Kinases -- Inhibitors of Upstream Inducers of STAT Activation. 000763392 506__ $$aAccess limited to authorized users. 000763392 520__ $$aThis volume, which includes contributions from leading scientists and clinicians in the field, provides definitive, state-of-the-art information on STAT inhibitors in a biological and clinical context. It gives an overview of the biology of the STAT family of transcription factors and their role in cancer etiology. Additionally, it describes the raft of therapeutic approaches being used to inhibit STATs in the context of various cancers, covering the full spectrum of therapeutic approaches to inhibiting STATs, and presenting emerging data from clinical trials. 000763392 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed October 11, 2016). 000763392 650_0 $$aCancer$$xMolecular aspects. 000763392 650_0 $$aTranscription factors. 000763392 650_0 $$aCellular signal transduction. 000763392 7001_ $$aWard, Alister C.,$$eeditor. 000763392 830_0 $$aCancer drug discovery and development. 000763392 852__ $$bebk 000763392 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-42949-6$$zOnline Access$$91397441.1 000763392 909CO $$ooai:library.usi.edu:763392$$pGLOBAL_SET 000763392 980__ $$aEBOOK 000763392 980__ $$aBIB 000763392 982__ $$aEbook 000763392 983__ $$aOnline 000763392 994__ $$a92$$bISE