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000763421 019__ $$a960902132$$a960976769$$a962436113
000763421 020__ $$a9789811020414$$q(electronic book)
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000763421 035__ $$aSP(OCoLC)ocn960738513
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000763421 050_4 $$aRC918.P58
000763421 08204 $$a616.6/1$$223
000763421 24500 $$aCystogenesis$$h[electronic resource] /$$cJong Hoon Park, Curie Ahn, editors.
000763421 260__ $$aSingapore :$$bSpringer,$$cc2016.
000763421 300__ $$a1 online resource.
000763421 336__ $$atext$$btxt$$2rdacontent
000763421 337__ $$acomputer$$bc$$2rdamedia
000763421 338__ $$aonline resource$$bcr$$2rdacarrier
000763421 4901_ $$aAdvances in experimental medicine and biology ;$$vvolume 933
000763421 500__ $$aIncludes index.
000763421 506__ $$aAccess limited to authorized users.
000763421 520__ $$aThis book covers the mechanisms of renal cyst development as well as the aberrant signaling pathways which are involved in Autosomal Dominant Polycystic Kidney Disease (ADPKD). ADPKD is a genetic disease in which cysts appear in the epithelial lining of both kidneys. End stage ADPKD patients experience renal failure and require dialysis or a renal transplantation. There are no specific targeted therapies for ADPKD currently available, making it important to understand the basic cellular mechanisms underlying the onset and progression of ADPKD, in order to identify potential therapeutic targets for the disease. Several therapeutic approaches that have been attempted to date are reviewed. This work provides a broad overview of ADPKD and highlights the key challenges currently faced by researchers in this field. Furthermore, it provides insight into ADPKD to facilitate the development of novel biomarkers for ADPKD and to direct future research into this challenging pathology. This book is suitable for clinicians who have encountered patients with ADPKD, for clinicians / researchers working in the field of ADPKD and more generally on the kidney and kidney related disorders and for students of medicine with an interest in internal medicine.
000763421 588__ $$aDescription based on print version record.
000763421 650_0 $$aPolycystic kidney disease.
000763421 7001_ $$aPark, Jong Hoon.
000763421 7001_ $$aAhn, Curie.
000763421 77608 $$iPrint version:$$z981102040X$$z9789811020407$$w(OCoLC)952157008
000763421 830_0 $$aAdvances in experimental medicine and biology ;$$vv. 933.
000763421 852__ $$bebk
000763421 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-981-10-2041-4$$zOnline Access$$91397441.1
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000763421 980__ $$aEBOOK
000763421 980__ $$aBIB
000763421 982__ $$aEbook
000763421 983__ $$aOnline
000763421 994__ $$a92$$bISE