Foreword 1; Foreword 2; Preface; Contents; Contributors; Introduction; 1 Healthcare Provisions in an Aging Society: U.S. Perspective; Abstract; Introduction; Changing Demographics; Age Change; Racial Changes and Immigration; Marital Status; Life Stressors; Income; Living Arrangements; Food Insecurity; Neighborhood Factors; Prevalence of Diseases; Introduction; Dementia; Disability; Depression; Cardiovascular Diseases; Cancer; Other; Medicare; Affordable Care Act ("Obamacare"); Proposed Benefits; Anticipated Issues; Primary Care and Access to Health Care; Medications

Future-Opportunities for the Pharmaceutical IndustryReferences; 2 Healthcare Provision in an Aging Society-The European Perspective; Abstract; Introduction; Older People in Europe; Demography of Aging in Europe; Prevalence of Diseases/Disability in Europe; Medication Use in Europe; An Introduction to Overprescribing and Underprescribing; Health Services for Older People; Discussion of Public Health Services with Individual Country Examples; Prescribing for Older People; National Guidelines and Cost-Effectiveness Arrangements; European Actions; European Medicines Agency

Actions on Representation of Older People in Clinical TrialsActions on Inappropriate Prescribing and Failure to Prescribe Appropriate Medications; Prescribing Toward End of Life; Conclusion/Discussion; References; 3 Healthcare Provisions in the Aging Society: Japanese Perspectives; Abstract; Introduction; Japan's Population is the Oldest in the World and is Getting Even Older; Universal Access and Excellent Population Health for Relatively Low Healthcare Costs; Japan's Healthcare System; Long-Term Care; How Population Aging Manifests Itself in Health Care and Communities?

Japan's Healthcare Reforms for 2025: Community-Based Integrated Care SystemConclusion; References; The Patient(s); 4 Old, Very Old and Frail; Abstract; Introduction; References; 5 Age and the Process of Aging; Abstract; Introduction; The Process of Aging; Age-Related Changes in Physiological Function; Age-Related Changes in Pharmacokinetics; Drug Absorption; First-Pass Metabolism and Bioavailability; Drug Distribution in the Body; Protein Binding; Drug Clearance; Liver; Kidney; Age-Related Changes in Pharmacodynamics; Anticoagulants; Cardiovascular Drugs; Calcium Channel Blockers

Beta-Blocking AgentsCentral Nervous System-Active Drugs; Variability in Response to Medicines; Information Needed for Appropriate Prescribing to Older Patients; Conclusion; References; 6 Comprehensive Geriatric Assessment; Abstract; Ten Target Areas for Geriatric Screening; Functional Assessment; Fall Assessment; Cognitive Assessment; Screening, Evaluation, and Differential Diagnosis; References; 7 Patients' Clinical Characteristics, Disease Experience, and Perception; Abstract; Introduction; Multimorbidity; Impact of Age on Health and Daily Functioning