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000763553 019__ $$a961205739$$a962434777
000763553 020__ $$a9783319414669$$q(electronic book)
000763553 020__ $$a3319414666$$q(electronic book)
000763553 020__ $$z9783319414645
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000763553 050_4 $$aRC1151.I45
000763553 08204 $$a616.07/9$$223
000763553 1001_ $$aChoukèr, Alexander,$$eauthor.
000763553 24504 $$aThe immune system in space :$$bare we prepared? /$$cAlexander Choukèr, Oliver Ullrich.
000763553 264_1 $$aCham, Switzerland :$$bSpringer,$$c[2016]
000763553 300__ $$a1 online resource.
000763553 336__ $$atext$$btxt$$2rdacontent
000763553 337__ $$acomputer$$bc$$2rdamedia
000763553 338__ $$aonline resource$$bcr$$2rdacarrier
000763553 4901_ $$aSpringerBriefs in space life sciences
000763553 504__ $$aIncludes bibliographical references.
000763553 5050_ $$aImmune system in evolution -- The immune system and man -- environment interaction from the clinical and from fundamental research perspectives -- The effects of Space and Space like conditions on Immune functions from the clinical and from fundamental perspective -- The upcoming venues: Individualized preventive or therapeutic measure, -- In vitro and in vivo tools to measure the efficacy of such measures -- Summary.
000763553 506__ $$aAccess limited to authorized users.
000763553 520__ $$aThis book gives insight into the mechanism of the immune system and the influence of the environment on earth. Further, the book explains the changes that occur in our immune system in the absence of gravity and their fundamental consequences. Several limiting factors for human health and performance in microgravity have been clearly identified as an unacceptable risk for long-term and interplanetary flights. Serious concerns arose whether spaceflight-associated immune system dysfunction ultimately precludes the expansion of human presence beyond Earth's orbit. The immune system has undergone many evolutionary steps to cope with a new and changing environment, but ̀spacè has not been evolutionary experienced before. Through endocrine orchestration of cell functions, cell to cell communications and intracellular mechanisms the human body and his immune system have an enormous capacity to adapt and react to altered environmental conditions. Thus, the special sensitivity to altered gravity renders the immune system an ideal biological model system to understand if and how gravity on Earth is required for the normal function of cells and cellular networks. It is one of the most fundamental challenges to find out, if our organism and our cellular machinery are able to live and to adequately perform without the gravity field of Earth. The book is written for immunologists and researchers in human physiology under normal and stressfull conditions.
000763553 588__ $$aOnline resource; title from PDF title page (viewed October 28, 2016).
000763553 650_0 $$aImmune system$$xEffect of space flight on.
000763553 7001_ $$aUllrich, Oliver,$$eauthor.
000763553 77608 $$iPrint version:$$tImmune System in Space.$$d[Place of publication not identified] : Springer Verlag 2016$$z9783319414645$$w(OCoLC)951761422
000763553 830_0 $$aSpringerBriefs in space life sciences.
000763553 852__ $$bebk
000763553 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-41466-9$$zOnline Access$$91397441.1
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000763553 980__ $$aEBOOK
000763553 980__ $$aBIB
000763553 982__ $$aEbook
000763553 983__ $$aOnline
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