Big data analytics in genomics / Ka-Chun Wong, editor.
Wong, Ka-Chun, editor.
2016
QA76.9.B45
Available Online

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Title Big data analytics in genomics / Ka-Chun Wong, editor.
ISBN 9783319412795 (electronic book)
3319412795 (electronic book)
9783319412788
3319412787
Published Switzerland : Springer, 2016.
Language English
Description 1 online resource.
Call Number QA76.9.B45
Dewey Decimal Classification 005.7
Summary This contributed volume explores the emerging intersection between big data analytics and genomics. Recent sequencing technologies have enabled high-throughput sequencing data generation for genomics resulting in several international projects which have led to massive genomic data accumulation at an unprecedented pace. To reveal novel genomic insights from this data within a reasonable time frame, traditional data analysis methods may not be sufficient or scalable, forcing the need for big data analytics to be developed for genomics. The computational methods addressed in the book are intended to tackle crucial biological questions using big data, and are appropriate for either newcomers or veterans in the field. This volume offers thirteen peer-reviewed contributions, written by international leading experts from different regions, representing Argentina, Brazil, China, France, Germany, Hong Kong, India, Japan, Spain, and the USA. In particular, the book surveys three main areas: statistical analytics, computational analytics, and cancer genome analytics. Sample topics covered include: statistical methods for integrative analysis of genomic data, computation methods for protein function prediction, and perspectives on machine learning techniques in big data mining of cancer. Self-contained and suitable for graduate students, this book is also designed for bioinformaticians, computational biologists, and researchers in communities ranging from genomics, big data, molecular genetics, data mining, biostatistics, biomedical science, cancer research, medical research, and biology to machine learning and computer science. Readers will find this volume to be an essential read for appreciating the role of big data in genomics, making this an invaluable resource for stimulating further research on the topic.
Access Note Access limited to authorized users.
Source of Description Description based on print version record.
Added Author Wong, Ka-Chun, editor.
Available in Other Form Big Data Analytics in Genomics.
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All Resources
Introduction to Statistical Methods for Integrative Analysis of Genomic Data
Robust Methods for Expression Quantitative Trait Loci Mapping
Causal Inference and Structure Learning of Genotype-Phenotype Networks using Genetic Variation
Genomic Applications of the Neyman-Pearson Classification Paradigm
Improving Re-annotation of Annotated Eukaryotic Genomes
State-of-the-art in Smith-Waterman Protein Database Search
A Survey of Computational Methods for Protein Function Prediction
Genome Wide Mapping of Nucleosome Position and Histone Code Polymorphisms in Yeast
Perspectives of Machine Learning Techniques in Big Data Mining of Cancer
Mining Massive Genomic Data for Therapeutic Biomarker Discovery in Cancer: Resources, Tools, and Algorithms
NGC Analysis of Somatic Mutations in Cancer Genomes
OncoMiner: A Pipeline for Bioinformatics Analysis of Exonic Sequence Variants in Cancer
A Bioinformatics Approach for Understanding Genotype-Phenotype Correlation in Breast Cancer.

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