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000763586 019__ $$a961411237$$a962436606
000763586 020__ $$a9783319305769$$q(electronic book)
000763586 020__ $$a331930576X$$q(electronic book)
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000763586 24500 $$aAlternating electric fields therapy in oncology :$$ba practical guide to clinical applications of tumor treating fields /$$cEric T. Wong, editor.
000763586 264_1 $$aSwitzerland :$$bSpringer,$$c[2016]
000763586 264_4 $$c©2016
000763586 300__ $$a1 online resource.
000763586 336__ $$atext$$btxt$$2rdacontent
000763586 337__ $$acomputer$$bc$$2rdamedia
000763586 338__ $$aonline resource$$bcr$$2rdacarrier
000763586 504__ $$aIncludes bibliographical references and index.
000763586 5050_ $$a1. Cell Biological Effects of Alternating Electric Fields -- 2. Fundamental Physics of Alternating Electric Fields Therapy -- 3. Biophysical Effects of Alternating Electric Fields -- 4. Computer Simulation of Alternating Electric Fields Therapy -- 5. Response Pattern and Modeling of Tumor-Treating Fields -- 6. Clinical Efficacy of Alternating Electric Fields for Recurrent Glioblastoma -- 7. Alternating Electric Fields in Clinical Practice with Emphasis on PRiDe Registry -- 8. Alternating Electric Fields Therapy for Newly Diagnosed Glioblastoma -- 9. Supportive Care in Patients Using Alternating Electric Fields Therapy -- 10. Future Directions for Alternating Electric Fields.
000763586 506__ $$aAccess limited to authorized users.
000763586 520__ $$aThis concise text provides a complete overview of alternating electric fields therapy -- also known as tumor treating fields -- for glioblastoma and other types of solid tumor malignancies. Readers are given a fundamental understanding of this novel anti-cancer treatment modality by learning from clinical trial data as well as the physical and cell biology effects on tumor cells when alternating electric fields are applied both in vitro and in vivo. Chapters illustrate the physics behind electric field propagation in space and other media. This is followed by a review of our current understanding of the electric field effects on dividing cells - including the disruption of cytokinesis, proper chromosome segregation and activation on the cell surface chaperons that induce immunogenic cell death. Data from phase III trials for the treatment of recurrent and newly diagnosed glioblastomas are included, as well as some of the ancillary post hoc analyses that were performed by various investigators. The remainder of the chapter covers other solid tumor malignancies, including non-small cell lung cancer, pancreatic cancer and ovarian cancer, as this treatment modality is being applied to systemic malignancies. Alternating Electric Fields Therapy in Oncology offers oncologists, neurologists, radiation oncologists, biomedical engineers, cell biologists and mitosis researchers the fundamentals needed for clinical practice.
000763586 588__ $$aDescription based on print version record.
000763586 650_0 $$aElectrotherapeutics.
000763586 650_0 $$aTumors$$xAlternative treatment.
000763586 650_0 $$aOncology.
000763586 7001_ $$aWong, Eric T.,$$eeditor.
000763586 77608 $$iPrint version:$$tAlternating electric fields therapy in oncology.$$d[Place of publication not identified] : Springer, 2016$$z3319305743$$w(OCoLC)936532847
000763586 852__ $$bebk
000763586 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-30576-9$$zOnline Access$$91397441.1
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000763586 980__ $$aEBOOK
000763586 980__ $$aBIB
000763586 982__ $$aEbook
000763586 983__ $$aOnline
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