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000763674 019__ $$a961934981$$a962436416
000763674 020__ $$a9783319437545$$q(electronic book)
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000763674 24500 $$aFundamentals of pediatric drug dosing /$$cIftekhar Mahmood, Gilbert Burckart, editors.
000763674 264_1 $$aCham, Switzerland :$$bAdis,$$c2016.
000763674 300__ $$a1 online resource.
000763674 336__ $$atext$$btxt$$2rdacontent
000763674 337__ $$acomputer$$bc$$2rdamedia
000763674 338__ $$aonline resource$$bcr$$2rdacarrier
000763674 506__ $$aAccess limited to authorized users.
000763674 520__ $$aFocused on pediatric physiology, pharmacology, pharmacokinetics and pharmacodynamics, this book illustrates the differences between the pediatric population and adults; knowledge of extreme importance not only during pediatric drug development but also in the clinical practice. Physicians, nurses, clinical pharmacologists, researchers and healthcare professionals will find this an invaluable resource. With the advent of pediatric exclusivity, and requirements to conduct clinical studies in children, an emphasis has been placed on finding a safe and efficacious dose of a drug in children. Children are not 'small adults', and drug dosing in this population requires special consideration. There are subtle physiological and biochemical differences among neonates, infants, children, adolescents and adults and dosing in pediatrics requires proper understanding of these factors. Furthermore, dosing in children, as in adults, should be based on pharmacokinetic and pharmacodynamic data. This is an evolving area, as pediatric pharmacokinetic studies are becoming mandatory for getting approval of new drugs in this population.
000763674 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed November 7, 2016).
000763674 650_0 $$aDrugs$$xDosage.
000763674 650_0 $$aPediatric pharmacology.
000763674 7001_ $$aMahmood, Iftekhar,$$eeditor.
000763674 7001_ $$aBurckart, Gilbert,$$eeditor.
000763674 77608 $$iPrint version:$$z3319437526$$z9783319437521$$w(OCoLC)952788819
000763674 852__ $$bebk
000763674 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-43754-5$$zOnline Access$$91397441.1
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000763674 983__ $$aOnline
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