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000764017 020__ $$a9783319073958$$q(electronic book)
000764017 020__ $$a3319073958$$q(electronic book)
000764017 020__ $$z9783319073941
000764017 0247_ $$a10.1007/978-3-319-07395-8$$2doi
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000764017 08204 $$a571.9/66$$223
000764017 24500 $$aTranscriptional control of lineage differentiation in immune cells /$$cWilfried Ellmeier, Ichiro Taniuchi, editors.
000764017 264_1 $$aCham :$$bSpringer,$$c[2014]
000764017 264_4 $$c©2014
000764017 300__ $$a1 online resource (viii, 331 pages) :$$billustrations.
000764017 336__ $$atext$$btxt$$2rdacontent
000764017 337__ $$acomputer$$bc$$2rdamedia
000764017 338__ $$aonline resource$$bcr$$2rdacarrier
000764017 4901_ $$aCurrent Topics in Microbiology and Immunology,$$x0070-217X ;$$vvolume 381
000764017 504__ $$aIncludes bibliographical references and index.
000764017 506__ $$aAccess limited to authorized users.
000764017 520__ $$aInsights into the regulation of immune cell lineage differentiation and specification as well as into the control of lineage integrity, stability and plasticity are of fundamental importance to understanding innate and adaptive immune responses. In this volume, leading experts provide an up-to-date and comprehensive overview of recent advances in the transcriptional control mechanisms and transcription factor networks that regulate these processes in a variety of different immune cell lineages. The chapters cover the regulation of T versus B cell lineage choice, discuss early B cell development and pre-B cell leukemia prevention, address transcriptional control mechanisms during Th differentiation, in regulatory T cells and iNKT cells, detail genomic switches in helper cell fate choice and plasticity, and highlight the role of the BTB-zinc finger family of transcription factors in T cells. Moreover, the chapters discuss transcriptional networks in DCs, NK cells and in innate lymphoid cells. Together, the reviews illustrate key transcriptional control mechanisms that regulate the development and function of immune cells and demonstrate the impressive advances made over the last decade.
000764017 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed September 19, 2014).
000764017 650_0 $$aT cells$$xDifferentiation.
000764017 650_0 $$aLymphocytes.
000764017 7001_ $$aEllmeier, Wilfried,$$eeditor.
000764017 7001_ $$aTaniuchi, Ichiro,$$eeditor.
000764017 77608 $$iPrint version:$$z9783319073941
000764017 830_0 $$aCurrent topics in microbiology and immunology ;$$vv.381.
000764017 852__ $$bebk
000764017 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-07395-8$$zOnline Access$$91397441.1
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000764017 983__ $$aOnline
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