000764109 000__ 05832cam\a2200541Ii\4500 000764109 001__ 764109 000764109 005__ 20230306142359.0 000764109 006__ m\\\\\o\\d\\\\\\\\ 000764109 007__ cr\cnunnnunnun 000764109 008__ 160919s2016\\\\xx\\\\\\ob\\\\001\0\eng\d 000764109 019__ $$a958863446$$a962725825 000764109 020__ $$a9781137540973$$q(electronic book) 000764109 020__ $$a1137540974$$q(electronic book) 000764109 020__ $$z9781137540966 000764109 0247_ $$a10.1057/978-1-137-54097-3$$2doi 000764109 035__ $$aSP(OCoLC)ocn958650899 000764109 035__ $$aSP(OCoLC)958650899$$z(OCoLC)958863446$$z(OCoLC)962725825 000764109 040__ $$aN$T$$beng$$erda$$epn$$cN$T$$dN$T$$dOCLCO$$dEBLCP$$dOCLCF$$dOCLCO$$dAZU$$dQCL$$dOCLCQ$$dYDX 000764109 049__ $$aISEA 000764109 050_4 $$aRC523 000764109 08204 $$a616.831$$223 000764109 24500 $$aEmerging technologies for diagnosing Alzheimer's disease :$$binnovating with care /$$cMarianne Boenink, Harro van Lente, Ellen Moors, editors. 000764109 264_1 $$a[Place of publication not identified] :$$bPalgrave Macmillan,$$c2016. 000764109 300__ $$a1 online resource. 000764109 336__ $$atext$$btxt$$2rdacontent 000764109 337__ $$acomputer$$bc$$2rdamedia 000764109 338__ $$aonline resource$$bcr$$2rdacarrier 000764109 347__ $$atext file$$bPDF$$2rda 000764109 4901_ $$aHealth, technology and society 000764109 504__ $$aIncludes bibliographical references and index. 000764109 5050_ $$aSeries Editors' Introduction; Acknowledgements; Contents; Notes on Contributors; List of Abbreviations; List of Figures ; List of Tables ; 1: Emerging Technologies for Diagnosing Alzheimer's Disease: Innovating withßCare; The Desirability ofßBiomarker Diagnostics ofßAlzheimer's Disease; Responsible Innovation; Innovating withßCare; Chapter Outline; References; Part I: Biomedical Research onßAlzheimer's Disease Diagnostics: Background andßTrends; 2: The Diagnosis andßTreatment ofßAlzheimer's: Are WeßBeing (Ir)responsible?; History ofßDiagnosis and Treatment. 000764109 5058_ $$aCurrent State ofßtheßAlzheimer's Field Crafting anßInnovative But Responsible Future; Early or Timely Diagnosis; Finding theßCure or Even anßEffective Therapy; A Case Study ofß'Irresponsibility'; Towards aßMore Responsible Future; New Approaches; References; 3: On Short Cuts: TheßComplexity ofßStudying theßEarly Diagnosis andßPrevention ofßAlzheimer's Disease; Two Decades, One Question; Around 1993; Around 2013; Even Milder Than Mild Cognitive Impairment: Prevention andßPrediction; Simplifications andßShort Cuts: OnßStudying Early Dementia; References. 000764109 5058_ $$a4: Biomarkers forßAlzheimer's Disease: Searching forßtheßMissing Link Between Biology andßClinic Biomarkers: Connecting Biology andßClinic; AD Biomarker Research: Development andßClinical Drivers; AD Biomarker Research inßPractice: TheßLeARN Project; Choosing Candidate Markers andßTechnological Platforms; Choosing Outcome Measures; Choices Related toßPatient Inclusion andßFollow-Up; Conclusion; References; 5: Care andßResponsibility inßBuilding Futures forßAlzheimer's Disease Research; Cohort Studies; The Sociality ofßCohorts; The MRC Cognitive Function andßAgeing Study. 000764109 5058_ $$aMediating theßCognitive Function andßAgeing Study Meeting theßCohort; Care andßResponsibility; References; Part II: Diagnosing Alzheimer's Disease: Current Practices; 6: Grey Matters: Emergent Biomarkers andßGood Alzheimer's Diagnostics; Background andßMethods; Current Practices ofßAD-Diagnostics inßtheßNetherlands: AßHeterogeneous Field; Good AD-Diagnostics: Differences; The Good Diagnosis: Five Diagnostic Values; Modes ofßDiagnosing: 'Pulling Out All theßStops' or 'Holding Back'; Distributing Differences; Distribution by Taxonomic Considerations. 000764109 5058_ $$aDistribution by Patients' Preferences Revisiting Current Practices ofßAD-Diagnostics: FromßGood toßBetter?; Value-Laden Taxonomies andßTaxonomy-Laden Preferences; Improving Practices ofßAD-Diagnostics; To Conclude: Emergent Biomarker Tools forßAD; References; 7: Understanding Cognitive Screening Tools: Navigating Uncertainty inßEveryday Clinical Practice; Methods; Clinician-Patient Interaction: Making ofßProvisionality; National Dementia CQUIN andßEarly Diagnosis: Constraining 'Care Work'; Discussion; References. 000764109 506__ $$aAccess limited to authorized users. 000764109 520__ $$aThis book explores international biomedical research and development on the early diagnosis of Alzheimer's disease. It offers timely, multidisciplinary reflections on the social and ethical issues raised by promises of early diagnostics and asks under which conditions emerging diagnostic technologies can be considered a responsible innovation. The initial chapters in this edited volume provide an overview and a critical discussion of recent developments in biomedical research on Alzheimer's disease. Subsequent contributions explore the values at stake in current practices of dealing with Alzheimer's disease and dementia, both within and outside the biomedical domain. Novel diagnostic technologies for Alzheimer's disease emerge in a complex and shifting field, full of controversies. Innovating with care requires a precise mapping of how concepts, values and responsibilities are filled in through the confrontation of practices. In doing so, the volume offers a practice-based approach of responsible innovation that is also applicable to other fields of innovation. 000764109 588__ $$aOnline resource; title from PDF title page (viewed October 3, 2016). 000764109 650_0 $$aAlzheimer's disease$$xDiagnosis. 000764109 7001_ $$aBoenink, Marianne,$$eeditor. 000764109 7001_ $$aLente, Harro van,$$d1962-$$eeditor. 000764109 7001_ $$aMoors, Ellen. 000764109 77608 $$iPrint version:$$z9781137540966 000764109 830_0 $$aHealth, technology, and society. 000764109 852__ $$bebk 000764109 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1057/978-1-137-54097-3$$zOnline Access$$91397441.1 000764109 909CO $$ooai:library.usi.edu:764109$$pGLOBAL_SET 000764109 980__ $$aEBOOK 000764109 980__ $$aBIB 000764109 982__ $$aEbook 000764109 983__ $$aOnline 000764109 994__ $$a92$$bISE