000764415 000__ 03779cam\a2200469Mi\4500 000764415 001__ 764415 000764415 005__ 20230306142415.0 000764415 006__ m\\\\\o\\d\\\\\\\\ 000764415 007__ cr\un\nnnunnun 000764415 008__ 161125s2016\\\\sz\\\\\\ob\\\\000\0\eng\d 000764415 019__ $$a963932059$$a965532944 000764415 020__ $$a9783319319643$$q(electronic book) 000764415 020__ $$a3319319647$$q(electronic book) 000764415 020__ $$z9783319319629 000764415 020__ $$z3319319620 000764415 035__ $$aSP(OCoLC)ocn964327719 000764415 035__ $$aSP(OCoLC)964327719$$z(OCoLC)963932059$$z(OCoLC)965532944 000764415 040__ $$aYDX$$beng$$cYDX$$dN$T$$dIDEBK$$dEBLCP$$dGW5XE$$dN$T 000764415 049__ $$aISEA 000764415 050_4 $$aRC514 000764415 08204 $$a616.89/8042$$223 000764415 1001_ $$aBulaeva, K. B.$$q(Kazima Bagdadovna) 000764415 24510 $$aGenomic architecture of schizophrenia across diverse genetic isolates$$h[electronic resource] :$$ba study of dagestan populations /$$cKazima Bulayeva, Oleg Bulayev, Stephen Glatt. 000764415 260__ $$aSwitzerland :$$bSpringer,$$c2016. 000764415 300__ $$a1 online resource. 000764415 336__ $$atext$$btxt$$2rdacontent 000764415 337__ $$acomputer$$bc$$2rdamedia 000764415 338__ $$aonline resource$$bcr$$2rdacarrier 000764415 504__ $$aIncludes bibliographical references. 000764415 5050_ $$aForeword; Preface; Contents; List of Figures; List of Tables; Introduction; References; Chapter 1: Current Problems of Complex Disease Genes Mapping; 1.1 General Problems of Complex Disease Genes Mapping; 1.2 Current Approaches of Schizophrenia Spectrum Disease Gene Mapping; 1.3 The Current State of Gene Mapping of Schizophrenia Spectrum Disorders; References; Chapter 2: Descriptions and Methods of Study in Selected Genetic Isolates of Dagestan; 2.1 History and Ethno-linguistic Diversity of Dagestan; 2.2 Genetic and Demographic Structure of the Selected Isolates 000764415 5058_ $$a2.3 Methods of Clinical Studies2.4 Molecular-Genetic Methods of Study; 2.5 Genetic and Statistical Methods of Experimental Data Analysis; References; Chapter 3: Selection of Populations for Mapping Genes of Complex Diseases; 3.1 Principles of Selection of Populations for Complex Disease Gene Mapping; 3.2 Ethnogenomic Structure of Dagestan Populations; 3.3 Genetic Epidemiology Study of Selected Genetic Isolates with the Aggregation of Schizophrenia Spectrum Disorders; 3.4 Gene Pool of Selected Isolates for Mapping Genes of Schizophrenia 000764415 5058_ $$a3.5 Role of Inbreeding in the Aggregation of a Schizophrenia and in Its Age of OnsetReferences; Chapter 4: Mapping Genes of Schizophrenia in Selected Dagestan Isolates; 4.1 Haplotype Analysis in Pedigrees Ascertained in the Isolates; 4.2 Genome-Wide Nonparametric Linkage Analysis of Schizophrenia in Selected Isolates; 4.3 Genome-Wide Parametric Linkage Analysis of Schizophrenia in Selected Isolates; 4.4 Cross-Population Analysis of Genome-Wide Linkages Scan for Schizophrenia in Selected Isolates; References; Chapter 5: Common Structural Genomic Variants in Linked with SCZ Regions 000764415 5058_ $$a5.1 Copy Number Variations and Runs of Homozygosity Analyses in Linked with SCZ Genomic Regions in Pedigrees of Selected Isola...5.2 Effect of Inbreeding on CNV and ROH Segments Sizes (Kb) and on Marker Numbers; 5.3 Cross-Isolate Study of Structural Genomic Variations in Linked with Schizophrenia Regions; References; Conclusions; Appendix: List of Genome-Wide Scanned Loci and Markers in Studied Dagestan Genetic Isolates (Weber/CHLC 9.0 Markers) 000764415 506__ $$aAccess limited to authorized users. 000764415 650_0 $$aSchizophrenia$$xGenetic aspects. 000764415 7001_ $$aBulayev, Oleg. 000764415 7001_ $$aGlatt, Stephen J. 000764415 77608 $$iPrint version:$$z3319319620$$z9783319319629$$w(OCoLC)942379379 000764415 852__ $$bebk 000764415 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-31964-3$$zOnline Access$$91397441.1 000764415 909CO $$ooai:library.usi.edu:764415$$pGLOBAL_SET 000764415 980__ $$aEBOOK 000764415 980__ $$aBIB 000764415 982__ $$aEbook 000764415 983__ $$aOnline 000764415 994__ $$a92$$bISE