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Preface; Contents; About the Editors; 1: Introduction to the Global Scenario of Marine Sponge Research; 1.1 Introduction; 1.2 Microbial Diversity of Marine Sponges Producing Bioactive Compounds; 1.3 Role of Molecular Markers in Deciphering the Sponge Diversity; 1.3.1 Allozymes; 1.3.2 Mitochondrial DNA (mtDNA); 1.3.3 Microsatellites; 1.3.4 Amplified Fragment Length Polymorphism (AFLP); 1.3.5 Nuclear DNA; 1.3.6 DNA Barcoding; 1.4 Sponge Molecular Microbiology; 1.5 Sponge Metagenomics; 1.6 Functional Metagenomics of Sponge and Its Symbionts.
1.7 Sponges Possess a Repertoire of Transient Receptor Potential Channels1.8 Cryptochrome-Based Photoreceptor System in Sponges; 1.9 Impacts of Marine Natural Products on Drug Discovery; 1.9.1 Sponge Natural Products Targeting Tumor-Associated Enzymes; 1.9.2 Sponge-Derived Proteases as Drug Targets; 1.9.3 Sponge-Derived Immunomodulatory Agents; 1.9.4 Sponge-Derived Natural Products as Sources of Therapeutic Agents; 1.9.5 Exceptional Bioactive Secondary Metabolites from Marine Sponges; 1.9.6 Defensive Enzymes from Sponge Endosymbionts.
1.10 Sponge Biomaterials in Tissue Engineering and Regenerative Medicine1.11 Cultivation of Sponge Symbionts; 1.12 Sponge Cell Culture and Apoptosis; 1.13 Future Perspectives and Avenues; References; 2: Global Constraints, Prospects, and Perspectives of Marine Sponge Research; 2.1 Introduction; 2.2 Current Research Limitations; 2.2.1 Sponge Microbial Symbioses; 2.2.2 Sponge Disease; 2.2.3 Climate Change on Marine Ecosystem; 2.3 Global Response and Conservation Efforts; 2.4 Recommendations and Conclusions; References; 3: Chemical Ecology of Marine Sponges; 3.1 What Is Chemical Ecology?
3.2 Marine Sponges3.3 Competition for Space; 3.4 Defence Against Predators; 3.5 Epibiotic Defence; 3.6 Defence Against Pathogens; 3.7 Conclusions; References; 4: Bioeroding Sponges in Aquaculture Systems; 4.1 Introduction; 4.2 Distribution of Boring Sponges; 4.3 Species Composition and Migration Pattern; 4.4 Conclusion; References; 5: Marine Sponge-Associated Actinobacteria and Their Biological Properties; 5.1 Introduction; 5.2 Marine Sponges; 5.3 Marine Sponge-Associated Actinobacteria; 5.4 Distributions of Marine Actinobacteria; 5.5 Diversity of Culturable Actinobacteria.
5.6 Bioactive Natural Products5.6.1 Antimicrobial Activity; 5.6.2 Anti-inflammatory Activity; 5.6.3 Antitumor Activity; 5.6.4 Anticancer Activity; 5.7 Conclusion; References; 6: Novel Insights on the Symbiotic Interactions of Marine Sponge-Associated Microorganisms: Marine Microbial Biotechnology Per ... ; 6.1 Introduction; 6.2 Bioactive Compounds from Marine Sponge-Associated Microbes; 6.2.1 Antibiotics; 6.2.2 Quinone and Quinolone Derivatives; 6.2.3 Peptides and Non-ribosomal Peptides; 6.2.4 Enzymes; 6.2.5 Polyketides; 6.2.6 Alkaloids; 6.2.7 Lactones; 6.2.8 Steroids; 6.2.9 Lipids.
1.7 Sponges Possess a Repertoire of Transient Receptor Potential Channels1.8 Cryptochrome-Based Photoreceptor System in Sponges; 1.9 Impacts of Marine Natural Products on Drug Discovery; 1.9.1 Sponge Natural Products Targeting Tumor-Associated Enzymes; 1.9.2 Sponge-Derived Proteases as Drug Targets; 1.9.3 Sponge-Derived Immunomodulatory Agents; 1.9.4 Sponge-Derived Natural Products as Sources of Therapeutic Agents; 1.9.5 Exceptional Bioactive Secondary Metabolites from Marine Sponges; 1.9.6 Defensive Enzymes from Sponge Endosymbionts.
1.10 Sponge Biomaterials in Tissue Engineering and Regenerative Medicine1.11 Cultivation of Sponge Symbionts; 1.12 Sponge Cell Culture and Apoptosis; 1.13 Future Perspectives and Avenues; References; 2: Global Constraints, Prospects, and Perspectives of Marine Sponge Research; 2.1 Introduction; 2.2 Current Research Limitations; 2.2.1 Sponge Microbial Symbioses; 2.2.2 Sponge Disease; 2.2.3 Climate Change on Marine Ecosystem; 2.3 Global Response and Conservation Efforts; 2.4 Recommendations and Conclusions; References; 3: Chemical Ecology of Marine Sponges; 3.1 What Is Chemical Ecology?
3.2 Marine Sponges3.3 Competition for Space; 3.4 Defence Against Predators; 3.5 Epibiotic Defence; 3.6 Defence Against Pathogens; 3.7 Conclusions; References; 4: Bioeroding Sponges in Aquaculture Systems; 4.1 Introduction; 4.2 Distribution of Boring Sponges; 4.3 Species Composition and Migration Pattern; 4.4 Conclusion; References; 5: Marine Sponge-Associated Actinobacteria and Their Biological Properties; 5.1 Introduction; 5.2 Marine Sponges; 5.3 Marine Sponge-Associated Actinobacteria; 5.4 Distributions of Marine Actinobacteria; 5.5 Diversity of Culturable Actinobacteria.
5.6 Bioactive Natural Products5.6.1 Antimicrobial Activity; 5.6.2 Anti-inflammatory Activity; 5.6.3 Antitumor Activity; 5.6.4 Anticancer Activity; 5.7 Conclusion; References; 6: Novel Insights on the Symbiotic Interactions of Marine Sponge-Associated Microorganisms: Marine Microbial Biotechnology Per ... ; 6.1 Introduction; 6.2 Bioactive Compounds from Marine Sponge-Associated Microbes; 6.2.1 Antibiotics; 6.2.2 Quinone and Quinolone Derivatives; 6.2.3 Peptides and Non-ribosomal Peptides; 6.2.4 Enzymes; 6.2.5 Polyketides; 6.2.6 Alkaloids; 6.2.7 Lactones; 6.2.8 Steroids; 6.2.9 Lipids.