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Preface; Acknowledgments; Contents; Contributors; 1 Introduction; Abstract; 1.1 Objectives; 1.2 Clinical Research; 1.2.1 Chapter 2 Methodology for Clinical Studies Investigating Chinese Medicine; 1.2.2 Chapter 3 Effectiveness Assessment of Chinese Medicine in Clinical Research; 1.2.3 Chapter 4 Placebo Controlled Trials in Acupuncture: Problems and Solutions; 1.3 Healthcare Data Acquisition and Analysis; 1.3.1 Chapter 5 Qualitative Interview for Chinese Medicine Research: Challenges and Prospects.
1.3.2 Chapter 6 A Need for Standard Data Collection Procedures in Studies on Traditional Chinese Medicine1.3.3 Chapter 7 Methods for Assessment of Interrater Reliability for Diagnosis and Intervention in Traditional Chinese Medicine Studies; 1.3.4 Chapter 8 Bioinformatics for Molecular Authentication of Chinese Medicinal Materials; 1.4 Laboratory Research; 1.4.1 Chapter 9 Proteomic Response Fingerprinting (ProReF) for Rapid Identification of Protein Targets for Chinese Medicine; 1.4.2 Chapter 10 Chinese Medicine in Neurological Diseases: Pharmacological Perspective.
1.4.3 Chapter 11 Effects of Chinese Medicinal Components of Chemokine Receptors: Theory, Results and Methodology1.5 Concluding Remarks; 2 Methodology for Clinical Study Investigating Chinese Medicine; Abstract; 2.1 Introduction to Basic Study Design; 2.1.1 Principles of Clinical Study Design; 2.1.1.1 Control; 2.1.1.2 Equalization; 2.1.1.3 Replication; 2.1.1.4 Blinding; 2.1.1.5 Ethics; 2.1.2 Basic Research Methods for Observational Studies; 2.1.2.1 Case Reports/Case Series Studies; 2.1.2.2 Cross-Sectional Studies; 2.1.2.3 Case-Control Studies; 2.1.2.4 Cohort Studies.
2.1.3 Basic Research Methods for Intervention Studies2.1.3.1 Randomized Controlled Trials; 2.1.3.2 Nonrandomized Controlled Trials; 2.1.4 Basic Research Methods for Comparative Effectiveness Research; 2.1.5 Basic Research Methods for Systematic Review and Meta-analysis; 2.2 Key Issues in Planning, Implementing, Analyzing, and Reporting a Clinical Study; 2.2.1 Planning; 2.2.1.1 Defining a Research Question; 2.2.1.2 Drafting the Study Protocol; 2.2.1.3 Registering the study; 2.2.2 Implementing; 2.2.2.1 Study Management; 2.2.2.2 Data Management; 2.2.3 Analyzing; 2.2.3.1 Steps of Data Analysis.
2.2.3.2 Basic Principles of Statistical Analysis2.2.4 Reporting; 2.2.4.1 Early Preparation for Publication; 2.2.4.2 Writing the Manuscript; 2.2.4.3 Publishing the Manuscript; Acknowledgments; References; 3 Effectiveness Assessment of Chinese Medicine in Clinical Research; Abstract; 3.1 Introduction; 3.2 Definition of Clinical Effectiveness of Interventions; 3.3 Factors Influencing Clinical Effectiveness: Risk of Bias and PICOS in Clinical Trials; 3.4 Considering CM Characteristics; 3.4.1 Effectiveness Assessment and Outcome Measurement.
1.3.2 Chapter 6 A Need for Standard Data Collection Procedures in Studies on Traditional Chinese Medicine1.3.3 Chapter 7 Methods for Assessment of Interrater Reliability for Diagnosis and Intervention in Traditional Chinese Medicine Studies; 1.3.4 Chapter 8 Bioinformatics for Molecular Authentication of Chinese Medicinal Materials; 1.4 Laboratory Research; 1.4.1 Chapter 9 Proteomic Response Fingerprinting (ProReF) for Rapid Identification of Protein Targets for Chinese Medicine; 1.4.2 Chapter 10 Chinese Medicine in Neurological Diseases: Pharmacological Perspective.
1.4.3 Chapter 11 Effects of Chinese Medicinal Components of Chemokine Receptors: Theory, Results and Methodology1.5 Concluding Remarks; 2 Methodology for Clinical Study Investigating Chinese Medicine; Abstract; 2.1 Introduction to Basic Study Design; 2.1.1 Principles of Clinical Study Design; 2.1.1.1 Control; 2.1.1.2 Equalization; 2.1.1.3 Replication; 2.1.1.4 Blinding; 2.1.1.5 Ethics; 2.1.2 Basic Research Methods for Observational Studies; 2.1.2.1 Case Reports/Case Series Studies; 2.1.2.2 Cross-Sectional Studies; 2.1.2.3 Case-Control Studies; 2.1.2.4 Cohort Studies.
2.1.3 Basic Research Methods for Intervention Studies2.1.3.1 Randomized Controlled Trials; 2.1.3.2 Nonrandomized Controlled Trials; 2.1.4 Basic Research Methods for Comparative Effectiveness Research; 2.1.5 Basic Research Methods for Systematic Review and Meta-analysis; 2.2 Key Issues in Planning, Implementing, Analyzing, and Reporting a Clinical Study; 2.2.1 Planning; 2.2.1.1 Defining a Research Question; 2.2.1.2 Drafting the Study Protocol; 2.2.1.3 Registering the study; 2.2.2 Implementing; 2.2.2.1 Study Management; 2.2.2.2 Data Management; 2.2.3 Analyzing; 2.2.3.1 Steps of Data Analysis.
2.2.3.2 Basic Principles of Statistical Analysis2.2.4 Reporting; 2.2.4.1 Early Preparation for Publication; 2.2.4.2 Writing the Manuscript; 2.2.4.3 Publishing the Manuscript; Acknowledgments; References; 3 Effectiveness Assessment of Chinese Medicine in Clinical Research; Abstract; 3.1 Introduction; 3.2 Definition of Clinical Effectiveness of Interventions; 3.3 Factors Influencing Clinical Effectiveness: Risk of Bias and PICOS in Clinical Trials; 3.4 Considering CM Characteristics; 3.4.1 Effectiveness Assessment and Outcome Measurement.