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1. Structure of the Heart and Cardiac Muscle 2. Energetics and Energy Production 3. Energy Utilization (Work and Heat) 4. The Contractile Proteins 5. The Cytoskeleton 6. Active State, Length-Tension Relationship, Cardiac Mechanics 7. Excitation-Contraction Coupling: Extracellular and Intracellular Calcium Cycles 8. Signal Transduction: Functional Signaling 9. Signal Transduction: Proliferative Signaling 10. Regulation of Cardiac Muscle Performance 11. The Heart as a Muscular Pump 12. The Working Heart 13. Cardiac Ion Channels 14. The Cardiac Action Potential 15. The Electrocardiogram 16. Arrhythmias 17. The Ischemic Heart 18. Heart Failure.

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