000771100 000__ 05045cam\a2200541Mi\4500 000771100 001__ 771100 000771100 005__ 20230306142435.0 000771100 006__ m\\\\\o\\d\\\\\\\\ 000771100 007__ cr\un\nnnunnun 000771100 008__ 161203s2016\\\\xx\\\\\\o\\\\\000\0\eng\d 000771100 019__ $$a964599590$$a965517929$$a967713563 000771100 020__ $$a3319480782 000771100 020__ $$z9783319480770 000771100 020__ $$a9783319480787$$q(electronic book) 000771100 0247_ $$a10.1007/978-3-319-48078-7$$2doi 000771100 035__ $$aSP(OCoLC)ocn965157310 000771100 035__ $$aSP(OCoLC)965157310$$z(OCoLC)964599590$$z(OCoLC)965517929$$z(OCoLC)967713563 000771100 040__ $$aEBLCP$$beng$$epn$$cEBLCP$$dOCLCQ$$dYDX$$dN$T$$dGW5XE$$dUPM$$dOCLCF$$dN$T 000771100 049__ $$aISEA 000771100 050_4 $$aQH450 000771100 08204 $$a610 000771100 1001_ $$aWallace, Rodrick. 000771100 24510 $$aGene Expression and Its Discontents :$$bthe Social Production of Chronic Disease. 000771100 250__ $$a2nd ed. 000771100 260__ $$aCham :$$bSpringer International Publishing,$$c2016. 000771100 300__ $$a1 online resource (344 pages) 000771100 336__ $$atext$$btxt$$2rdacontent 000771100 337__ $$acomputer$$bc$$2rdamedia 000771100 338__ $$aonline resource$$bcr$$2rdacarrier 000771100 347__ $$atext file$$bPDF$$2rda 000771100 500__ $$a11.6.2 The Body mass Index. 000771100 504__ $$aIncludes bibliographical references and index. 000771100 5050_ $$aPreface; Contents; 1 Introduction ; 1.1 Toward New Tools; 1.2 Epigenetic Epidemiology; 1.3 Ecosystem Resilience; 1.3.1 Comorbid Disorders; 1.3.2 Some Cognitive Modules of Human Biology; 1.3.3 Cognition as ``Language'': an Introduction; 1.3.4 A Multiplicity of Resilience Topologies; 1.3.5 In Summary; 1.4 A First Survey of the Obesity Pandemic in the USA; 2 Models of Development; 2.1 The Spinglass Model; 2.2 Shifting Perspective: Cognition as an Information Source; 3 Groupoid Symmetries; 3.1 The First Level; 3.2 The Second Level; 3.3 Spontaneous Symmetry Breaking; 3.4 A Biological Example. 000771100 5058_ $$a4 Epigenetic Catalysis4.1 The Basic Idea; 4.2 Rate Distortion Dynamics; 4.3 More Topology; 4.4 Inherited Epigenetic Memory; 4.5 Multiple Processes; 4.6 ``Coevolutionary'' Development; 4.7 Multiple Models; 4.8 Epigenetic Focus; 5 Developmental Disorders; 5.1 Network Information Theory; 5.2 Embedding Ecosystems as Information Sources; 5.3 Ecosystems Farm Development; 5.4 A Simple Probability Argument; 5.5 Developmental Shadows; 5.6 Epigenetic Programming of Artificial Systemsfor Biotechnology; 6 An Interim Perspective; 7 The Obesity Pandemic in the USA; 7.1 Introduction. 000771100 5058_ $$a7.2 Stress and the HPA Axis7.3 HPA Axis Cognition; 7.4 Interacting Information Sources; 7.5 A HPA Axis Model; 7.6 Psychosocial Stress, Occupational Control, and Weight Gain; 7.7 Obesity as a Developmental Disorder; 7.8 Recent Trajectories of Structured Stress in the USA; 7.9 Confronting the Obesity Epidemic; 8 Heart Disease; 8.1 Coronary Heart Disease in the USA; 8.1.1 Cognition, Immune Cognition, and Culture; 8.1.2 Punctuated Interpenetration: Adapting to Pathogenic Hierarchy; 8.1.3 Implications for Intervention; 8.2 Thrombogenesis; 8.2.1 Control Theory: The Data Rate Theorem. 000771100 5058_ $$a8.2.2 The Information Cost of Hemostatic Regulation8.2.3 Control Failure Dynamics; 8.2.4 Cognitive Symmetry Breaking; 8.2.5 Onset of ``Turbulent'' Clot Growth; 8.2.6 Implications for Intervention; 9 Cancer; 9.1 A Developmental Model; 9.2 Environmental Insult and Regulatory Failure; 10 Autoimmune Disorders; 10.1 Introduction; 10.2 Nonorthogonal Eigenmodes of Immune Cognition; 10.3 Circadian and Other Cycles; 10.4 The Retina of the Immune Response; 10.5 Circadian-Hormonal Cycle Synergism; 10.6 The Cognitive HPA Axis; 10.7 Phase Transitions of Interacting Information Systems. 000771100 5058_ $$a10.8 Autoimmune Disease10.9 An Application to Asthma; 10.10 Images of Pathogenic Social Hierarchy; 11 Demoralization and Obesity in Upper Manhattan; 11.1 Introduction; 11.2 Methods; 11.2.1 Recruitment of the Mothers; 11.2.2 Prenatal Questionnaire; 11.2.3 Socioeconomic Data; 11.2.4 Chronic Community Stress Index; 11.3 Data Analysis; 11.4 Modeling Demoralization and Chronic Stress; 11.5 Results; 11.5.1 Demoralization and Chronic Stress; 11.5.2 Signal Transduction Modeling; 11.5.3 Body Mass Index; 11.5.4 Household Deprivation; 11.6 Discussion; 11.6.1 The Asymmetric Inverted ``U'' Curve. 000771100 506__ $$aAccess limited to authorized users. 000771100 520__ $$aThis volume examines a class of probability models describing how epigenetic context affects gene expression and organismal development, using the asymptotic limit theorems of information theory in a highly formal manner. 000771100 588__ $$aDescription based on print version record. 000771100 650_0 $$aGene expression. 000771100 650_0 $$aChronic diseases. 000771100 7001_ $$aWallace, Deborah. 000771100 77608 $$iPrint version:$$aWallace, Rodrick.$$tGene Expression and Its Discontents : The Social Production of Chronic Disease.$$dCham : Springer International Publishing, ©2016$$z9783319480770 000771100 852__ $$bebk 000771100 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-48078-7$$zOnline Access$$91397441.1 000771100 909CO $$ooai:library.usi.edu:771100$$pGLOBAL_SET 000771100 980__ $$aEBOOK 000771100 980__ $$aBIB 000771100 982__ $$aEbook 000771100 983__ $$aOnline 000771100 994__ $$a92$$bISE