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Table of Contents
Preface; Contents; 1 Obesity and Risk of Cancer: An Introductory Overview; Abstract; 1 Introduction; 2 Definition and Assessment of Obesity; 3 Obesity and Cancer-Weighing the Evidence: A Historical Perspective; 3.1 Colorectal Cancer; 3.2 Breast Cancer; 3.3 Esophageal Cancer; 3.4 Kidney Cancer; 3.5 Pancreatic Cancer; 3.6 Endometrial Cancer; 3.7 Liver Cancer; 3.8 Prostate Cancer; 3.9 Ovarian Cancer; 3.10 Gallbladder Cancer; 4 Potential Mechanisms and Pathways for the Association of Obesity with Cancer Risk; 5 Burden of Cancer Attributable to Obesity on a Population Level; 6 Conclusions
3.1 General Obesity and Mortality in Colorectal Cancer Patients3.2 Abdominal Obesity and Mortality in Colorectal Cancer Patients; 3.3 Obesity and Treatment Outcomes in Colorectal Cancer Patients; 3.4 Summary and Recommendation on Weight Management in Colorectal Cancer Patients; 4 Weight Change in Adulthood and Risk of Colorectal Cancer; 4.1 Weight Gain and Colorectal Cancer Risk; 4.2 Weight Loss and Colorectal Cancer Risk; 4.3 Summary on the Effects of Weight Change on Colorectal Cancer Risk; 5 Relations of Childhood and Adolescent Obesity to Risks of Colorectal Cancer and Colorectal Adenoma
6 Potential Biological Mechanisms Linking Obesity to Colorectal Cancer6.1 Insulin Resistance, Hyperinsulinemia and Insulin-like Growth Factor; 6.2 Chronic Inflammation; 6.3 Hypoadiponectinemia and Hyperleptinemia; 6.4 Sex Hormones; 6.5 Summary of Potential Biological Mechanisms; 7 Summary and Future Research; References; 3 Obesity and Breast Cancer; Abstract; 1 Introduction; 2 Body Size Across the Life Course and Breast Cancer Risk; 2.1 Childhood Body Size; 2.2 General Adiposity in Adulthood and Breast Cancer; 2.2.1 BMI and Premenopausal Breast Cancer Risk
2.2.2 Premenopausal BMI and Postmenopausal Breast Cancer Risk2.2.3 Postmenopausal BMI and Breast Cancer Risk; 3 BMI and Breast Cancer-Specific Survival; 4 Weight Changes; 4.1 Weight Gain and Risk of Premenopausal Breast Cancer; 4.2 Weight Gain and Postmenopausal Breast Cancer Risk; 4.3 Weight Loss and Breast Cancer Risk; 4.4 Weight Change and Breast Cancer-Specific Survival; 5 Visceral Adiposity: Waist Circumference/Waist-Hip Ratio; 5.1 WC/WHR and Risk of Premenopausal Breast Cancer; 5.2 WC/WHR and Risk of Postmenopausal Breast Cancer; 5.3 WC and WHR and Breast Cancer-Specific Survival
3.1 General Obesity and Mortality in Colorectal Cancer Patients3.2 Abdominal Obesity and Mortality in Colorectal Cancer Patients; 3.3 Obesity and Treatment Outcomes in Colorectal Cancer Patients; 3.4 Summary and Recommendation on Weight Management in Colorectal Cancer Patients; 4 Weight Change in Adulthood and Risk of Colorectal Cancer; 4.1 Weight Gain and Colorectal Cancer Risk; 4.2 Weight Loss and Colorectal Cancer Risk; 4.3 Summary on the Effects of Weight Change on Colorectal Cancer Risk; 5 Relations of Childhood and Adolescent Obesity to Risks of Colorectal Cancer and Colorectal Adenoma
6 Potential Biological Mechanisms Linking Obesity to Colorectal Cancer6.1 Insulin Resistance, Hyperinsulinemia and Insulin-like Growth Factor; 6.2 Chronic Inflammation; 6.3 Hypoadiponectinemia and Hyperleptinemia; 6.4 Sex Hormones; 6.5 Summary of Potential Biological Mechanisms; 7 Summary and Future Research; References; 3 Obesity and Breast Cancer; Abstract; 1 Introduction; 2 Body Size Across the Life Course and Breast Cancer Risk; 2.1 Childhood Body Size; 2.2 General Adiposity in Adulthood and Breast Cancer; 2.2.1 BMI and Premenopausal Breast Cancer Risk
2.2.2 Premenopausal BMI and Postmenopausal Breast Cancer Risk2.2.3 Postmenopausal BMI and Breast Cancer Risk; 3 BMI and Breast Cancer-Specific Survival; 4 Weight Changes; 4.1 Weight Gain and Risk of Premenopausal Breast Cancer; 4.2 Weight Gain and Postmenopausal Breast Cancer Risk; 4.3 Weight Loss and Breast Cancer Risk; 4.4 Weight Change and Breast Cancer-Specific Survival; 5 Visceral Adiposity: Waist Circumference/Waist-Hip Ratio; 5.1 WC/WHR and Risk of Premenopausal Breast Cancer; 5.2 WC/WHR and Risk of Postmenopausal Breast Cancer; 5.3 WC and WHR and Breast Cancer-Specific Survival