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000771112 020__ $$a9783319499024$$q(electronic book)
000771112 020__ $$a3319499025$$q(electronic book)
000771112 020__ $$z9783319499017
000771112 035__ $$aSP(OCoLC)ocn965196172
000771112 035__ $$aSP(OCoLC)965196172
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000771112 24500 $$aReviews of physiology, biochemistry and pharmacology.$$n172 /$$cedited by Bernd Nilius, Pieter de Tombe, Thomas Gudermann, Reinhard Jahn, Roland Lill, Ole H. Petersen.
000771112 264_1 $$aCham, Switzerland :$$bSpringer,$$c2016.
000771112 300__ $$a1 online resource.
000771112 336__ $$atext$$btxt$$2rdacontent
000771112 337__ $$acomputer$$bc$$2rdamedia
000771112 338__ $$aonline resource$$bcr$$2rdacarrier
000771112 5050_ $$aHepatic Stellate Cells in Liver Fibrosis and siRNA-Based Therapy; 1 Introduction; 2 Hepatic Stellate Cells; 2.1 Functions of HSC in the Normal and in the Injured Liver; 2.1.1 Storage of Vitamin A; 2.1.2 Extracellular Matrix (ECM) Synthesis and Degradation; 2.1.3 Liver Development and Regeneration; 2.1.4 Immunoregulation Function; 2.2 HSC and Liver Fibrosis; 3 Resolution of Fibrosis; 3.1 Anti-fibrotic Therapeutic Approaches; 3.2 Gene Therapy; 3.3 RNA Interference; 3.3.1 Barriers of siRNA Delivery and Therapy; 4 Lipid-Based siRNA Delivery; 4.1 Cationic Liposomes; 4.2 Neutral Lipids
000771112 5058_ $$a4.3 Stable Nucleic Acid-Lipid Particles (SNALPs)5 Polymeric Nanoparticles; 5.1 Polyethyleneimine; 5.2 Poly(Lactic-co-Glycolic Acid) (PLGA); 5.3 Chitosan; 5.4 Cyclodextrin; 6 SiRNA-Nanotherapeutics and Liver Fibrosis; 7 Conclusion; References; Exosomes: From Functions in Host-Pathogen Interactions and Immunity to Diagnostic and Therapeutic Opportunities; 1 Introduction; 2 Exosome Biogenesis and Secretion; 3 Exosome Molecular Composition; 4 Exosome as Immunomodulators; 4.1 Exosomes and Innate Immunity; 4.2 Exosomes and Acquired Immunity; 5 Exosomes in Host-Pathogen Interactions
000771112 5058_ $$a5.1 Exosomes in Fungal Infection5.2 Exosomes in Parasitic Infection; 5.3 Exosomes in Viral Infection; 5.4 Exosomes in Bacterial Infection; 6 Exosomes in Disease States: Applications in Diagnostic, Vaccine, and Therapeutic Approaches; 6.1 Exosomes: Promising Diagnostic Tools; 6.2 Exosome-Based Vaccination: An Encouraging Approach; 6.3 Exosomes: Promising New Conveyors of Therapeutic Molecules; 7 Conclusion; References; The Stress-Response MAP Kinase Signaling in Cardiac Arrhythmias; 1 Introduction; 2 Electrical Remodeling and Arrhythmia Development; 3 Excitation-Contraction Coupling
000771112 5058_ $$a4 Arrhythmia Initiation and Abnormal Ca2+ Triggered Activities5 Arrhythmia Stabilization; 6 MAPKs and Arrhythmia Development; 7 MAPKs Activation and Pathological Remodeling in the Heart; 8 MAPK Family; 9 Conclusions and Implications; References
000771112 506__ $$aAccess limited to authorized users.
000771112 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed January 5, 2017).
000771112 650_0 $$aHuman physiology.
000771112 650_0 $$aMolecular biology.
000771112 650_0 $$aMetabolism$$xDisorders.
000771112 7001_ $$aNilius, B.,$$eeditor.
000771112 7001_ $$aTombe, Pieter de,$$eeditor.
000771112 7001_ $$aGudermann, Thomas,$$eeditor.
000771112 7001_ $$aJahn, Reinhard,$$d1950-$$eeditor.
000771112 7001_ $$aLill, Roland,$$eeditor.
000771112 7001_ $$aPetersen, Ole,$$eeditor.
000771112 852__ $$bebk
000771112 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-49902-4$$zOnline Access$$91397441.1
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000771112 980__ $$aEBOOK
000771112 980__ $$aBIB
000771112 982__ $$aEbook
000771112 983__ $$aOnline
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